CD163 Mouse Monoclonal Antibody [Clone ID: OTI2G12]

USD 360.00


Availability*
In Stock

Size
    • 100 ul


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Specifications

Product Data
Clone Name OTI2G12
Applications IF, IHC, WB
Recommend Dilution WB 1:1000, IHC 1:150, IF 1:100
Reactivity Human
Host Mouse
Isotype IgG1
Clonality Monoclonal
Immunogen Full length human recombinant protein of human CD163(NP_004235) produced in HEK293T cell.
Formulation PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration 1 mg/ml
Purification Purified from cell culture supernatant by affinity chromatography
Predicted Protein Size 125.3 kDa
Gene Name CD163 molecule
Background The protein encoded by this gene is a member of the scavenger receptor cysteine-rich (SRCR) superfamily, and is exclusively expressed in monocytes and macrophages. It functions as an acute phase-regulated receptor involved in the clearance and endocytosis of hemoglobin/haptoglobin complexes by macrophages, and may thereby protect tissues from free hemoglobin-mediated oxidative damage. This protein may also function as an innate immune sensor for bacteria and inducer of local inflammation. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Aug 2011]
Synonyms M130; MM130; SCARI1
Reference Data
Protein Families Druggable Genome, Secreted Protein, Transmembrane

Citations (1)

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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