IL2 (NM_000586) Human Recombinant Protein

CAT#: TP790117

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Purified recombinant protein of Human interleukin 2 (IL2), Tag free, secretory expressed in CHO cells, 100ug



  View other "IL2" proteins (8)

USD 468.00


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    • 100 ug


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Specifications

Product Data
Description Purified recombinant protein of Human interleukin 2 (IL2), Tag free, secretory expressed in CHO cells, 100ug
Species Human
Expression Host CHO
Expression cDNA Clone or AA Sequence A DNA sequence from TrueORF clone, RC210013, encoding the region Ala21-Thr153 of IL2
Tag Tag Free
Predicted MW 15.4 kDa
Concentration >50 ug/mL as determined by microplate BCA method
Purity > 95% as determined by SDS-PAGE and Coomassie blue staining
Buffer Lyophilized from a sterile solution containing phosphate buffer, pH7.4.
Endotoxin < 1 EU per 1 µg of the protein by the LAL
Storage Store at -80°C.
Stability Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Reference Data
RefSeq NP_000577
Locus ID 3558
UniProt ID P60568, Q0GK43
Cytogenetics 4q27
Refseq Size 822
Refseq ORF 459
Synonyms IL-2; lymphokine; TCGF
Summary This gene is a member of the interleukin 2 (IL2) cytokine subfamily which includes IL4, IL7, IL9, IL15, IL21, erythropoietin, and thrombopoietin. The protein encoded by this gene is a secreted cytokine produced by activated CD4+ and CD8+ T lymphocytes, that is important for the proliferation of T and B lymphocytes. The receptor of this cytokine (IL2R) is a heterotrimeric protein complex whose gamma chain is also shared by IL4 and IL7. The expression of this gene in mature thymocytes is monoallelic, which represents an unusual regulatory mode for controlling the precise expression of a single gene. The targeted disruption of a similar gene in mice leads to ulcerative colitis-like disease, which suggests an essential role of this gene in the immune response to antigenic stimuli. [provided by RefSeq, Sep 2020]
Protein Families Druggable Genome, Secreted Protein
Protein Pathways Allograft rejection, Autoimmune thyroid disease, Cytokine-cytokine receptor interaction, Graft-versus-host disease, Jak-STAT signaling pathway, T cell receptor signaling pathway, Type I diabetes mellitus

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IL2 mouse monoclonal antibody,clone OTI2C9
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