IL2 (NM_000586) Human Recombinant Protein

CAT#: TP720012

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Recombinant protein of human interleukin 2 (IL2), Pro22-Thr153


 Product Datasheet for 'TP720012'

  View other "IL2" proteins (12)

USD 299.00


Availability*
2 Weeks

Size
    • 10 ug


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Specifications

Product Data
Description Recombinant protein of human interleukin 2 (IL2), Pro22-Thr153
Species Human
Expression Host E. coli
Tag Tag Free
Predicted MW 15.5 kDa
Concentration Resuspend the protein to the desired concentration in proper buffer.
Purity >95% as determined by SDS-PAGE and Coomassie blue staining
Buffer Lyophilized from a 0.2 µM filtered solution of 20mM HAc-NaAc, 150mM NaCl, pH 4.0.
Bioactivity ED50 is less than 0.1 ng/ml as determined by the dose-dependent stimulation of murine CTLL-2 cells. Specific Activity of 1.0 x 107 IU/ mg.
Endotoxin < 0.1 EU per µg protein as determined by LAL test
Reference Data
RefSeq NP_000577
Locus ID 3558
Refseq Size 822
Cytogenetics 4q27
Refseq ORF 459
Synonyms IL-2; lymphokine; TCGF
Summary The protein encoded by this gene is a secreted cytokine that is important for the proliferation of T and B lymphocytes. The receptor of this cytokine is a heterotrimeric protein complex whose gamma chain is also shared by interleukin 4 (IL4) and interleukin 7 (IL7). The expression of this gene in mature thymocytes is monoallelic, which represents an unusual regulatory mode for controlling the precise expression of a single gene. The targeted disruption of a similar gene in mice leads to ulcerative colitis-like disease, which suggests an essential role of this gene in the immune response to antigenic stimuli. [provided by RefSeq, Jul 2008]
Protein Families Druggable Genome, Secreted Protein
Protein Pathways Allograft rejection, Autoimmune thyroid disease, Cytokine-cytokine receptor interaction, Graft-versus-host disease, Jak-STAT signaling pathway, T cell receptor signaling pathway, Type I diabetes mellitus

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Other Versions

Frequently bought together (1)
IL2 mouse monoclonal antibody,clone OTI2C9
    • 100 ul

USD 360.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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