SGSH (NM_000199) Human Recombinant Protein

CAT#: TP308270

Recombinant protein of human N-sulfoglucosamine sulfohydrolase (SGSH)

Product images

Specifications

Product Data

• Description: Recombinant protein of human N-sulfoglucosamine sulfohydrolase (SGSH)
• Species: Human
• Expression Host: HEK293T
• Expression cDNA Clone or AA Sequence: Recombinant protein was produced with TrueORF clone, RC208270. Click on the TrueORF clone link to view cDNA and protein sequences.
• Tag: C-MYC/DDK
• Predicted MW: 54.6 kDa
• Concentration: >50 ug/mL as determined by microplate BCA method
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol. Store at –80C. Avoid repeated freeze-thaw cycles. Stable for 3 months from receipt of products under proper storage and handling conditions.
• Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.

Reference Data

• RefSeq: NP_000190
• Locus ID: 6448
• Refseq Size: 2770
• Cytogenetics: 17q25.3
• Refseq ORF: 1509
• Synonyms: HSS; MPS3A; SFMD
• Summary: This gene encodes the enzyme sulfamidase; one of several enzymes involved in the lysosomal degradation of heparan sulfate. Mutations in this gene are associated with the lysosomal storage disease mucopolysaccaridosis IIIA, also known as Sanfilippo syndrome A, which results from impaired degradation of heparan sulfate. Transcripts of varying sizes have been reported but their biological validity has not been determined. [provided by RefSeq, Jun 2017]
• Protein Families: Druggable Genome
• Protein Pathways: Glycosaminoglycan degradation, Metabolic pathways, Lysosome