SGSH (NM_000199) Human Recombinant Protein

CAT#: TP308270

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Recombinant protein of human N-sulfoglucosamine sulfohydrolase (SGSH)


 Product Datasheet for 'TP308270'

  View other "SGSH" proteins (4)

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USD 748.00


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Size
    • 20 ug


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Specifications

Product Data
Description Recombinant protein of human N-sulfoglucosamine sulfohydrolase (SGSH)
Species Human
Expression Host HEK293T
Expression cDNA Clone or AA Sequence Recombinant protein was produced with TrueORF clone, RC208270. Click on the TrueORF clone link to view cDNA and protein sequences.
Tag C-Myc/DDK
Predicted MW 54.6 kDa
Concentration >50 ug/mL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Preparation Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
Reference Data
RefSeq NP_000190
Locus ID 6448
Refseq Size 2770
Cytogenetics 17q25.3
Refseq ORF 1506
Synonyms HSS; MPS3A; SFMD
Summary This gene encodes the enzyme sulfamidase; one of several enzymes involved in the lysosomal degradation of heparan sulfate. Mutations in this gene are associated with the lysosomal storage disease mucopolysaccaridosis IIIA, also known as Sanfilippo syndrome A, which results from impaired degradation of heparan sulfate. Transcripts of varying sizes have been reported but their biological validity has not been determined. [provided by RefSeq, Jun 2017]
Protein Families Druggable Genome
Protein Pathways Glycosaminoglycan degradation, Lysosome, Metabolic pathways

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