Hap1 (NM_177982) Rat Tagged ORF Clone Lentiviral Particle
CAT#: RR200388L3V
- LentiORF®
Lenti ORF particles, Hap1 (Myc-DDK-tagged ORF) - Rat huntingtin-associated protein 1 (Hap1), transcript variant 2, 200ul, >10^7 TU/mL
Lentiviral Particles: mGFP w/ Puro
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Specifications
Product Data | |
Type | Rat Tagged ORF Clone Lentiviral Particle |
Tag | Myc-DDK |
Symbol | Hap1 |
Synonyms | HAP1-A; HAP1-B |
Mammalian Cell Selection | Puromycin |
Vector | pLenti-C-Myc-DDK-P2A-Puro |
ACCN | NM_177982 |
ORF Size | 1887 bp |
Sequence Data |
The ORF insert of this clone is exactly the same as(RR200388).
|
OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_177982.2 |
RefSeq Size | 3184 bp |
RefSeq ORF | 1890 bp |
Locus ID | 29430 |
UniProt ID | P54256 |
Cytogenetics | 10q31 |
Gene Summary | Huntington's disease (HD), a neurodegenerative disorder characterized by loss of striatal neurons, is caused by an expansion of a polyglutamine tract in the HD protein huntingtin. This gene encodes a protein that is homologous to the human huntingtin-associated protein 1. The human protein interacts with huntingtin, with two cytoskeletal proteins (dynactin and pericentriolar autoantigen protein 1), and with a hepatocyte growth factor-regulated tyrosine kinase substrate. The interactions with cytoskeletal proteins and a kinase substrate suggest a role for this protein in vesicular trafficking or organelle transport. Two transcripts encoding different isoforms have been identified. [provided by RefSeq, Jul 2008] |
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