SAE1 (NM_001145713) Human Tagged ORF Clone Lentiviral Particle
CAT#: RC226908L4V
- LentiORF®
Lenti ORF particles, SAE1 (mGFP-tagged) - Human SUMO1 activating enzyme subunit 1 (SAE1), transcript variant 2, 200ul, >10^7 TU/mL
Lentiviral Particles: DDK w/ Puro
AAV Particle: DDK
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Specifications
Product Data | |
Type | Human Tagged ORF Clone Lentiviral Particle |
Tag | mGFP |
Symbol | SAE1 |
Synonyms | AOS1; HSPC140; SUA1; UBLE1A |
Mammalian Cell Selection | Puromycin |
Vector | pLenti-C-mGFP-P2A-Puro |
ACCN | NM_001145713 |
ORF Size | 897 bp |
Sequence Data |
The ORF insert of this clone is exactly the same as(RC226908).
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OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_001145713.1 |
RefSeq ORF | 900 bp |
Locus ID | 10055 |
UniProt ID | Q9UBE0 |
Cytogenetics | 19q13.32 |
Protein Pathways | Ubiquitin mediated proteolysis |
MW | 32.9 kDa |
Gene Summary | Posttranslational modification of proteins by the addition of the small protein SUMO (see SUMO1; MIM 601912), or sumoylation, regulates protein structure and intracellular localization. SAE1 and UBA2 (MIM 613295) form a heterodimer that functions as a SUMO-activating enzyme for the sumoylation of proteins (Okuma et al., 1999 [PubMed 9920803]).[supplied by OMIM, Mar 2010] |
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