Acid sphingomyelinase (SMPD1) (NM_001007593) Human Tagged ORF Clone Lentiviral Particle
CAT#: RC219816L3V
- LentiORF®
Lenti ORF particles, SMPD1 (Myc-DDK-tagged)-Human sphingomyelin phosphodiesterase 1, acid lysosomal (SMPD1), transcript variant 2, 200ul, >10^7 TU/mL
Lentiviral Particles: mGFP w/ Puro
AAV Particle: DDK
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Specifications
Product Data | |
Type | Human Tagged ORF Clone Lentiviral Particle |
Tag | Myc-DDK |
Symbol | Acid sphingomyelinase |
Synonyms | ASM; ASMASE; NPD |
Mammalian Cell Selection | Puromycin |
Vector | pLenti-C-Myc-DDK-P2A-Puro |
ACCN | NM_001007593 |
ORF Size | 1890 bp |
Sequence Data |
The ORF insert of this clone is exactly the same as(RC219816).
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OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_001007593.1 |
RefSeq Size | 2341 bp |
RefSeq ORF | 1893 bp |
Locus ID | 6609 |
UniProt ID | P17405 |
Cytogenetics | 11p15.4 |
Protein Families | Druggable Genome, Transmembrane |
Protein Pathways | Lysosome, Metabolic pathways, Sphingolipid metabolism |
MW | 69.81 kDa |
Gene Summary | The protein encoded by this gene is a lysosomal acid sphingomyelinase that converts sphingomyelin to ceramide. The encoded protein also has phospholipase C activity. Defects in this gene are a cause of Niemann-Pick disease type A (NPA) and Niemann-Pick disease type B (NPB). Multiple transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2010] |
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