mu Crystallin (CRYM) (NM_001888) Human Tagged ORF Clone Lentiviral Particle
CAT#: RC218123L3V
- LentiORF®
Lenti ORF particles, CRYM (Myc-DDK tagged) - Human crystallin, mu (CRYM), transcript variant 1, 200ul, >10^7 TU/mL
Lentiviral Particles: DDK mGFP mGFP w/ Puro
AAV Particle: DDK
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Specifications
Product Data | |
Type | Human Tagged ORF Clone Lentiviral Particle |
Tag | Myc-DDK |
Symbol | mu Crystallin |
Synonyms | DFNA40; THBP |
Mammalian Cell Selection | Puromycin |
Vector | pLenti-C-Myc-DDK-P2A-Puro |
ACCN | NM_001888 |
ORF Size | 942 bp |
Sequence Data |
The ORF insert of this clone is exactly the same as(RC218123).
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OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_001888.2 |
RefSeq Size | 1559 bp |
RefSeq ORF | 945 bp |
Locus ID | 1428 |
UniProt ID | Q14894 |
Cytogenetics | 16p12.2 |
Domains | ODC_Mu_crystall |
MW | 33.8 kDa |
Gene Summary | Crystallins are separated into two classes: taxon-specific and ubiquitous. The former class is also called phylogenetically-restricted crystallins. The latter class constitutes the major proteins of vertebrate eye lens and maintains the transparency and refractive index of the lens. This gene encodes a taxon-specific crystallin protein that binds NADPH and has sequence similarity to bacterial ornithine cyclodeaminases. The encoded protein does not perform a structural role in lens tissue, and instead it binds thyroid hormone for possible regulatory or developmental roles. Mutations in this gene have been associated with autosomal dominant non-syndromic deafness. [provided by RefSeq, Sep 2014] |
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