Ribonuclease Inhibitor (RNH1) (NM_203385) Human Tagged ORF Clone Lentiviral Particle
CAT#: RC213589L4V
- LentiORF®
Lenti ORF particles, RNH1 (mGFP-tagged)-Human ribonuclease/angiogenin inhibitor 1 (RNH1), transcript variant 4, 200ul, >10^7 TU/mL
Lentiviral Particles: DDK w/ Puro
AAV Particle: DDK
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Specifications
Product Data | |
Type | Human Tagged ORF Clone Lentiviral Particle |
Tag | mGFP |
Symbol | Ribonuclease Inhibitor |
Synonyms | RAI; RNH |
Mammalian Cell Selection | Puromycin |
Vector | pLenti-C-mGFP-P2A-Puro |
ACCN | NM_203385 |
ORF Size | 1383 bp |
Sequence Data |
The ORF insert of this clone is exactly the same as(RC213589).
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OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_203385.1, NP_976319.1 |
RefSeq Size | 1884 bp |
RefSeq ORF | 1386 bp |
Locus ID | 6050 |
UniProt ID | P13489 |
Cytogenetics | 11p15.5 |
MW | 50 kDa |
Gene Summary | Placental ribonuclease inhibitor (PRI) is a member of a family of proteinaceous cytoplasmic RNase inhibitors that occur in many tissues and bind to both intracellular and extracellular RNases (summarized by Lee et al., 1988 [PubMed 3219362]). In addition to control of intracellular RNases, the inhibitor may have a role in the regulation of angiogenin (MIM 105850). Ribonuclease inhibitor, of 50,000 Da, binds to ribonucleases and holds them in a latent form. Since neutral and alkaline ribonucleases probably play a critical role in the turnover of RNA in eukaryotic cells, RNH may be essential for control of mRNA turnover; the interaction of eukaryotic cells with ribonuclease may be reversible in vivo.[supplied by OMIM, Jul 2010] |
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