EXT1 (NM_000127) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC200644L2V

Lenti ORF particles, EXT1 (mGFP-tagged) - Human exostosin 1 (EXT1), 200ul, >10^7 TU/mL

Specifications

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: mGFP
• Symbol: EXT1
• Synonyms: EXT; LGCR; LGS; TRPS2; TTV
• Mammalian Cell Selection: None
• Vector: pLenti-C-mGFP
• ACCN: NM_000127
• ORF Size: 2238 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC200644).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_000127.2
• RefSeq Size: 3376 bp
• RefSeq ORF: 2241 bp
• Locus ID: 2131
• UniProt ID: Q16394
• Cytogenetics: 8q24.11
• Domains: Exostosin
• Protein Families: Druggable Genome, Transmembrane
• Protein Pathways: Heparan sulfate biosynthesis, Metabolic pathways
• MW: 86.3 kDa
• Gene Summary: This gene encodes an endoplasmic reticulum-resident type II transmembrane glycosyltransferase involved in the chain elongation step of heparan sulfate biosynthesis. Mutations in this gene cause the type I form of multiple exostoses. [provided by RefSeq, Jul 2008]