Neuraminidase (NEU1) (NM_000434) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC200386L1V

  • LentiORF®

Lenti ORF particles, NEU1 (Myc-DDK tagged) - Human sialidase 1 (lysosomal sialidase) (NEU1), 200ul, >10^7 TU/mL

ORF Plasmid: DDK tGFP

Lentiviral Particles: DDK DDK w/ Puro mGFP mGFP w/ Puro


Biosafety Sheet

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USD 1,236.00

2 Weeks*

Size
    • 200 ul

Product Images

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Specifications

Product Data
Type Human Tagged ORF Clone Lentiviral Particle
Tag Myc-DDK
Symbol Neuraminidase
Synonyms NANH; NEU; SIAL1
Mammalian Cell Selection None
Vector pLenti-C-Myc-DDK
ACCN NM_000434
ORF Size 1245 bp
Sequence Data
The ORF insert of this clone is exactly the same as(RC200386).
OTI Disclaimer The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
OTI Annotation This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
Reference Data
RefSeq NM_000434.2
RefSeq Size 2088 bp
RefSeq ORF 1248 bp
Locus ID 4758
UniProt ID Q99519
Cytogenetics 6p21.33
Domains BNR
Protein Families Druggable Genome, Transmembrane
Protein Pathways Lysosome, Other glycan degradation, Sphingolipid metabolism
MW 45.5 kDa
Gene Summary The protein encoded by this gene is a lysosomal enzyme that cleaves terminal sialic acid residues from substrates such as glycoproteins and glycolipids. In the lysosome, this enzyme is part of a heterotrimeric complex together with beta-galactosidase and cathepsin A (the latter is also referred to as 'protective protein'). Mutations in this gene can lead to sialidosis, a lysosomal storage disease that can be type 1 (cherry red spot-myoclonus syndrome or normosomatic type), which is late-onset, or type 2 (the dysmorphic type), which occurs at an earlier age with increased severity. [provided by RefSeq, Jul 2008]

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.