ARFGEF3 (NM_020340) Human Untagged Clone

CAT#: SC318713

KIAA1244 (untagged)-Human KIAA1244 (KIAA1244)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: ARFGEF3
• Synonyms: A7322; BIG3; C6orf92; dJ171N11.1; KIAA1244; PPP1R33
• Vector: pCMV6 series
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_020340, the custom clone sequence may differ by one or more nucleotides
  ATGGAAGAAATCCTGAGGAAGCTGCAGAAGGAGGCGTCCGGGAGCAAGTACAAAGCCATC
  AAGGAGAGCTGCACCTGGGCCCTGGAAACTCTAGGTGGTCTGGATACCATTGTCAAGATC
  CCTCCACATGTACTGAGGGAGAAATGCCTGCTGCCTCTCCAGTTGGCTTTGGAATCCAAG
  AATGTGAAGCTGGCCCAACATGCTTTGGCAGGGATGCAGAAGCTTCTGTCGGAAGAGAGG
  TTTGTATCCATGGAAACAGATTCTGATGAGAAGCAGCTGCTCAATCAGATACTGAATGCC
  GTGAAAGTGACGCCTTCGCTCAACGAGGACCTGCAGGTGGAAGTGATGAAGGTTTTACTA
  TGCATCACCTACACGCCAACATTTGATCTGAATGGGAGTGCCGTGCTGAAGATCGCGGAG
  GTGTGCATTGAGACGTACATAAGCAGCTGTCACCAGCGTAGCATAAACACTGCTGTGCGG
  GCAACTCTCAGTCAAATGCTGAGTGACTTGACTTTACAGTTACGACAGAGGCAGGAGAAT
  ACGATAATTGAAAACCCAGATGTCCCACAGGATTTCGGGAATCAAGGGTCAACAGTAGAG
  TCCCTCTGTGATGATGTTGTCTCTGTACTCACCGTCCTGTGTGAGAAGCTGCAAGCCGCC
  ATAAATGACAGCCAGCAGCTGCAGCTTCTCTACCTGGAGTGCATCCTGTCTGTGCTCAGC
  AGCTCCTCCTCCTCCATGCACCTGCACAGGCGCTTCACGGACCTGATCTGGAAAAACCTC
  TGCCCTGCTCTCATCGTGATCTTGGGGAATCCAATTCATGACAAAACCATCACCTCTGCT
  CACACCAGCAGCACCAGTACCAGCCTGGAGTCGGACTCTGCGTCTCCGGGAGTGTCTGAC
  CACGGCCGAGGATCAGGCTGCTCCTGCACTGCGCCGGCCCTGAGCGGACCTGTGGCTCGG
  ACTATCTATTACATCGCAGCCGAGCTGGTCCGGCTGGTGGGGTCTGTGGACTCCATGAAG
  CCCGTGCTCCAGTCCCTCTACCACCGAGTGCTGCTCTACCCCCCACCCCAGCACCGGGTG
  GAAGCCATCAAAATAATGAAAGAGATACTTGGGAGCCCACAGCGTCTCTGTGACTTGGCA
  GGACCCAGCTCCACTGAATCAGAGTCCAGAAAAAGATCAATTTCAAAAAGAAAGTCTCAT
  CTGGATCTCCTCAAACTCATCATGGATGGCATGACCGAAGCATGCATCAAGGGTGGCATC
  GAAGCTTGCTATGCAGCCGTGTCCTGTGTCTGCACCTTGCTGGGTGCCCTGGATGAGCTC
  AGCCAGGGGAAGGGCTTGAGCGAAGGTCAGGTGCAACTGCTGCTTCTGCGCCTTGAGGAG
  CTGAAGGATGGGGCTGAGTGGAGCCGAGATTCCATGGAGATCAATGAGGCTGACTTCCGC
  TGGCAGCGGCGAGTGCTGTCCTCAGAACACACGCCGTGGGAGTCAGGGAACGAGAGGAGC
  CTTGACATCAGCATCAGTGTCACCACAGACACAGGCCAGACCACTCTCGAGGGAGAGTTG
  GGTCAGACTACACCCGAGGACCATTCGGGAAACCACAAGAACAGTCTCAAGTCGCCAGCC
  ATCCCAGAGGGTAAGGAGACGCTGAGCAAAGTATTGGAAACAGAGGCGGTAGACCAGCCA
  GATGTCGTGCAGAGAAGCCACACGGTCCCTTACCCTGACATAACTAACTTCCTGTCAGTA
  GACTGCAGGACAAGGTCCTATGGATCTAGGTATAGTGAGAGCAATTTTAGCGTTGATGAC
  CAAGACCTTTCTAGGACAGAGTTTGATTCCTGTGATCAGTACTCTATGGCAGCAGAAAAG
  GACTCGGGCAGGTCCGACGTGTCAGACATTGGGTCGGACAACTGTTCACTAGCCGATGAA
  GAGCAGACACCCCGGGACTGCCTAGGCCACCGGTCCCTGCGAACTGCCGCCCTGTCTCTA
  AAACTGCTGAAGAACCAGGAGGCGGATCAGCACAGCGCCAGGCTGTTCATACAGTCCCTG
  GAAGGCCTCCTCCCTCGGCTCCTGTCTCTCTCCAATGTAGAGGAGGTGGACACCGCTCTG
  CAGAACTTTGCCTCTACTTTCTGCTCAGGCATGATGCACTCTCCTGGCTTTGACGGGAAT
  AGCAGCCTCAGCTTCCAGATGCTGATGAACGCAGACAGCCTCTACACAGCTGCACACTGC
  GCCCTGCTCCTCAACCTGAAGCTCTCCCACGGTGACTACTACAGGAAGCGGCCGACCCTG
  GCGCCAGGCGTGATGAAGGACTTCATGAAGCAGGTGCAGACCAGCGGCGTGCTGATGGTC
  TTCTCTCAGGCCTGGATTGAGGAGCTCTACCATCAGGTGCTCGACAGGAACATGCTTGGA
  GAGGCTGGCTATTGGGGCAGCCCAGAAGATAACAGCCTTCCCCTCATCACAATGCTGACC
  GATATTGACGGCTTAGAGAGCAGTGCCATTGGTGGCCAGCTGATGGCCTCGGCTGCTACA
  GAGTCTCCTTTCGCCCAGAGCAGGAGAATTGATGACTCCACAGTGGCAGGCGTGGCATTT
  GCTCGCTATATTCTGGTGGGCTGCTGGAAGAACTTGATCGATACTTTATCAACCCCACTG
  ACTGGTCGAATGGCGGGGAGCTCCAAAGGGCTGGCCTTCATTCTGGGAGCTGAAGGCATC
  AAAGAGCAGAACCAGAAGGAGCGGGACGCCATCTGCATGAGCCTCGACGGGCTGCGGAAA
  GCCGCACGGCTGAGCTGCGCTCTAGGCGTTGCTGCTAACTGCGCCTCAGCCCTTGCCCAG
  ATGGCAGCTGCCTCCTGTGTCCAAGAAGAAAAAGAAGAGAGGGAGGCCCAAGAACCCAGT
  GATGCCATCACACAAGTGAAACTAAAAGTGGAGCAGAAACTGGAGCAGATTGGGAAGGTG
  CAGGGGGTGTGGCTGCACACTGCCCACGTCTTGTGCATGGAGGCCATCCTCAGCGTAGGC
  CTGGAGATGGGAAGCCACAACCCGGACTGCTGGCCACACGTGTTCAGGGTGTGTGAATAC
  GTGGGCACCCTGGAGCACAACCACTTCAGCGATGGTGCCTCGCAGCCCCCTCTGACCATC
  AGCCAGCCCCAGAAGGCCACTGGAAGCGCTGGCCTCCTTGGGGACCCCGAGTGTGAGGGC
  TCGCCCCCCGAGCACAGCCCGGAGCAGGGGCGCTCCCTGAGCACGGCCCCTGTCGTCCAG
  CCCCTGTCCATCCAGGACCTCGTCCGGGAAGGCAGCCGGGGTCGGGCCTCCGACTTCCGC
  GGCGGGAGCCTCATGAGCGGGAGCAGCGCGGCCAAGGTGGTGCTCACCCTCTCCACGCAA
  GCCGACAGGCTCTTTGAAGATGCTACGGATAAGTTGAACCTCATGGCCTTGGGAGGTTTT
  CTTTACCAGCTGAAGAAAGCATCGCAGTCTCAGCTTTTCCATTCTGTTACAGATACAGTT
  GATTACTCTCTGGCAATGCCAGGAGAAGTTAAATCCACTCAAGACCGAAAAAGCGCCCTC
  CACCTGTTCCGCCTGGGGAATGCCATGCTGAGGATTGTGCGGAGCAAAGCACGGCCCCTG
  CTCCACGTGATGCGCTGCTGGAGCCTTGTGGCCCCACACCTGGTGGAGGCTGCTTGCCAT
  AAGGAAAGACATGTGTCTCAGAAGGCTGTTTCCTTCATCCATGACATACTGACAGAAGTC
  CTCACTGACTGGAATGAGCCACCTCATTTTCACTTCAATGAAGCACTCTTCCGACCTTTC
  GAGCGCATTATGCAGCTGGAATTGTGTGATGAGGACGTCCAAGACCAGGTTGTCACATCC
  ATTGGTGAGCTGGTTGAAGTGTGTTCCACGCAGATCCAGTCGGGATGGAGACCCTTGTTC
  AGTGCCCTGGAAACAGTGCATGGCGGGAACAAGTCAGAGATGAAGGAGTACCTGGTTGGT
  GACTACTCCATGGGAAAAGGCCAAGCTCCAGTGTTTGATGTATTTGAAGCTTTTCTCAAT
  ACTGACAACATCCAGGTCTTTGCTAATGCAGCCACTAGCTACATCATGTGCCTTATGAAG
  TTTGTCAAAGGACTGGGGGAGGTGGACTGTAAAGAGATTGGAGACTGTGCCCCAGCACCC
  GGAGCCCCGTCCACAGACCTGTGCCTCCCGGCCCTGGATTACCTCAGGCGCTGCTCTCAG
  TTATTGGCCAAAATCTACAAAATGCCCTTGAAGCCAATATTCCTTAGTGGGAGACTTGCC
  GGCTTGCCTCGAAGACTTCAGGAACAGTCAGCCAGCAGTGAGGATGGAATTGAATCAGTC
  CTGTCTGATTTTGATGATGACACCGGTCTGATAGAAGTCTGGATAATCCTGCTGGAGCAG
  CTGACAGCGGCTGTGTCCAATTGTCCACGGCAGCACCAACCACCAACTCTGGATTTACTC
  TTTGAGCTGTTGAGAGATGTGACGAAAACACCAGGACCAGGGTTTGGTATCTATGCAGTG
  GTTCACCTCCTCCTTCCTGTGATGTCCGTTTGGCTCCGCCGGAGCCATAAAGACCATTCC
  TACTGGGATATGGCCTCTGCCAATTTCAAGCACGCTATTGGTCTGTCCTGTGAGCTGGTG
  GTGGAGCACATTCAAAGCTTTCTACATTCAGATATCAGGTACGAGAGCATGATCAATACC
  ATGCTGAAGGACCTCTTTGAGTTGCTGGTCGCCTGTGTGGCCAAGCCCACTGAAACCATC
  TCCAGAGTGGGCTGCTCCTGTATTAGATACGTCCTTGTGACAGCGGGCCCTGTGTTCACT
  GAGGAGATGTGGAGGCTTGCCTGCTGTGCCCTGCAAGATGCGTTCTCTGCCACACTCAAG
  CCAGTGAAGGACCTGCTGGGCTGCTTCCACAGCGGCACGGAGAGCTTCAGCGGGGAAGGC
  TGCCAGGTGCGAGTGGCGGCCCCGTCCTCCTCCCCAAGTGCCGAGGCCGAGTACTGGCGC
  ATCCGAGCCATGGCCCAGCAGGTGTTTATGCTGGACACCCAGTGCTCACCAAAGACACCA
  AACAACTTTGACCACGCTCAGTCCTGCCAGCTCATTATTGAGCTGCCTCCTGATGAAAAA
  CCAAATGGACACACCAAGAAAAGCGTGTCTTTCAGGGAAATTGTGGTGAGCCTGCTGTCT
  CATCAGGTGTTACTCCAGAACTTATATGACATCTTGTTAGAAGAGTTTGTCAAAGGCCCC
  TCTCCTGGAGAGGAAAAGACGATACAAGTGCCAGAAGCCAAGCTGGCTGGCTTCCTCAGA
  TACATCTCTATGCAGAACTTGGCAGTCATATTCGACCTGCTGCTGGACTCTTATAGGACT
  GCCAGGGAGTTTGACACCAGCCCCGGGCTGAAGTGCCTGCTGAAGAAAGTGTCTGGCATC
  GGGGGCGCCGCCAACCTCTACCGCCAGTCTGCGATGAGCTTTAACATTTATTTCCACGCC
  CTGGTGTGTGCTGTTCTCACCAATCAAGAAACCATCACGGCCGAGCAAGTGAAGAAGGTC
  CTTTTTGAGGACGACGAGAGAAGCACGGATTCTTCCCAGCAGTGTTCATCTGAGGATGAA
  GACATCTTTGAGGAAACCGCCCAGGTCAGCCCCCCGAGAGGCAAGGAGAAGAGACAGTGG
  CGGGCACGGATGCCCTTGCTCAGCGTCCAGCCTGTCAGCAACGCAGATTGGGTGTGGCTG
  GTCAAGAGGCTGCACAAGCTGTGCATGGAACTGTGCAACAACTACATCCAGATGCACTTG
  GACCTGGAGAACTGTATGGAGGAGCCTCCCATCTTCAAGGGCGACCCGTTCTTCATCCTG
  CCCTCCTTCCAGTCCGAGTCATCCACCCCATCCACCGGGGGCTTCTCTGGGAAAGAAACC
  CCTTCCGAGGATGACAGAAGCCAGTCCCGGGAGCACATGGGCGAGTCCCTGAGCCTGAAG
  GCCGGTGGTGGGGACCTGCTGCTGCCCCCCAGCCCCAAAGTGGAGAAGAAGGATCCCAGC
  CGGAAGAAGGAGTGGTGGGAGAATGCGGGGAACAAAATCTACACCATGGCAGCCGACAAG
  ACCATTTCAAAGTTGATGACCGAATACAAAAAGAGGAAACAGCAGCACAACCTGTCCGCG
  TTCCCCAAAGAGGTCAAAGTGGAGAAGAAAGGAGAGCCACTGGGTCCCAGGGGCCAGGAC
  TCCCCGCTGCTTCAGCGTCCCCAGCACTTGATGGACCAAGGGCAAATGCGGCATTCCTTC
  AGCGCAGGCCCCGAGCTGCTGCGACAGGACAAGAGGCCCCGCTCAGGCTCCACCGGGAGC
  TCCCTCAGTGTCTCGGTGAGAGACGCAGAAGCACAGATCCAGGCATGGACCAACATGGTG
  CTAACAGTTCTCAATCAGATTCAGATTCTCCCAGACCAGACCTTCACGGCCCTCCAGCCC
  GCAGTGTTCCCGTGCATCAGTCAGCTGACCTGTCACGTGACCGACATCAGAGTTCGCCAG
  GCTGTGAGGGAGTGGCTGGGCAGGGTGGGCCGTGTCTATGACATCATTGTG
  
• Restriction Sites: Please inquire
• ACCN: NM_020340
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_020340.3, NP_065073.3
• RefSeq Size: 8847 bp
• RefSeq ORF: 6534 bp
• Locus ID: 57221
• UniProt ID: Q5TH69
• Cytogenetics: 6q23.3-q24.1
• Gene Summary: Participates in the regulation of systemic glucose homeostasis, where it negatively regulates insulin granule biogenesis in pancreatic islet beta cells (By similarity). Also regulates glucagon granule production in pancreatic alpha cells (By similarity). Inhibits nuclear translocation of the transcriptional coregulator PHB2 and may enhance estrogen receptor alpha (ESR1) transcriptional activity in breast cancer cells (PubMed:19496786).[UniProtKB/Swiss-Prot Function]