IGFBP5 (NM_000599) Human Untagged Clone

CAT#: SC127161

IGFBP5 (untagged)-Human insulin-like growth factor binding protein 5 (IGFBP5)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: IGFBP5
• Synonyms: IBP5
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC127161 sequence for NM_000599 edited (data generated by NextGen Sequencing)
  ATGGTGTTGCTCACCGCGGTCCTCCTGCTGCTGGCCGCCTATGCGGGGCCGGCCCAGAGC
  CTGGGCTCCTTCGTGCACTGCGAGCCCTGCGACGAGAAAGCCCTCTCCATGTGCCCCCCC
  AGCCCCCTGGGCTGCGAGCTGGTCAAGGAGCCGGGCTGCGGCTGCTGCATGACCTGCGCC
  CTGGCCGAGGGGCAGTCGTGCGGCGTCTACACCGAGCGCTGCGCCCAGGGGCTGCGCTGC
  CTCCCCCGGCAGGACGAGGAGAAGCCGCTGCACGCCCTGCTGCACGGCCGCGGGGTTTGC
  CTCAACGAAAAGAGCTACCGCGAGCAAGTCAAGATCGAGAGAGACTCCCGTGAGCACGAG
  GAGCCCACCACCTCTGAGATGGCCGAGGAGACCTACTCCCCCAAGATCTTCCGGCCCAAA
  CACACCCGCATCTCCGAGCTGAAGGCTGAAGCAGTGAAGAAGGACCGCAGAAAGAAGCTG
  ACCCAGTCCAAGTTTGTCGGGGGAGCCGAGAACACTGCCCACCCCCGGATCATCTCTGCA
  CCTGAGATGAGACAGGAGTCTGAGCAGGGCCCCTGCCGCAGACACATGGAGGCTTCCCTG
  CAGGAGCTCAAAGCCAGCCCACGCATGGTGCCCCGTGCTGTGTACCTGCCCAATTGTGAC
  CGCAAAGGATTCTACAAGAGAAAGCAGTGCAAACCTTCCCGTGGCCGCAAGCGTGGCATC
  TGCTGGTGCGTGGACAAGTACGGGATGAAGCTGCCAGGCATGGAGTACGTTGACGGGGAC
  TTTCAGTGCCACACCTTCGACAGCAGCAACGTTGAGTGA
  
  Clone variation with respect to NM_000599.3
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_000599 unedited
  ACGACTCACTATAGGGCGGCCGCGAATTCGGCACGAGGGTTTTCACCCTTCTCCGGACTT
  CGCGTAGAACCTGCGAATTTCGAAGAGGAGGTGGCAAAGTGGGAGAAAAGAGGTGTTAGG
  GTTTGGGGTTTTTTTGTTTTTGTTTTTGTTTTTTAATTTCTTGATTTCAACATTTTCTCC
  CACCCTCTCGGCTGCAGCCAACGCCTCTTACCTGTTCTGCGGCGCCGCGCACCGCTGGCA
  GCTGAGGGTTAGAAAGCGGGGTGTATTTTAGATTTTAAGCAAAAATTTTAAAGATAAATC
  CATTTTTCTCTCCCACCCCCAACGCCATCTCCACTGCATCCGATCTCATTATTTCGGTGG
  TTGCTTGGGGGTGAACAATTTTGTGGCTTTTTTTCCCCTATAATTCTGACCCGCTCAGGC
  TTGAGGGTTTCTCCGGCCTCCGCTCACTGCGTGCACCTGGCGCTGCCCTGCTTCCCCCAA
  CCTGTTGCAAGGCTTTAATTCTTGCAACTGGGACCTGCTCGCAGGCACCCCAGCCCTCCA
  CCTCTCTCTACATTNTTGCAAGTGTCTGGGGGAGGGCACCTGCTCTACCTGCCAGATATT
  TTAAAACAAAAACAAAAACAAAAAAATCTCCGGGGGGCCCTCTTGGCCCCTTTATCCCTG
  CACTCTCGCTCTCCTGCNCCCACCCCGAGTAAAGGGGGCGACTAANAGAGATGGTGTTGC
  TCACCGCGGTCCTTCTGCTGCTGGCCGNCTATGCNGNGCCCGCCCANAGCCCTGGCTNCT
  TCGTGCACTGCGAGCCCTGCGACGAGAAAGCCCTCTCCTGTGCCCCCCCAGCCCCCTGGC
  TGCNNAGCTGTCAAGGAGCCCGNCTGCNGCTGCTGCATGACCTGCGCCCTGNCCGAAGGG
  CATTNGTGCGGGGTCTACACCGATCGCTGGCCCAGGGGCTGGGCTGCCTCCCCCGCAGAA
  CAAGGAAACCGCTGCCCCCCT
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_000599 unedited
  GACCGCGGCCGCAATTTANAGTCGAGTTTTTTTTTTTTTTTTTTGCCCCACAAAAAACTG
  AGTTTATTGCTCACGGGAAACTCTGCCTCGAGGCAGGCAAAAATGCTATTACGGGTTGTA
  TTAGGAGAATATGGGTTTTCTCAGTTTTCCCAGAATGAGGAAGCTCCTCAATGCCCCTAT
  AGGAACTACTTTGAAAAGTTAATGCAAACCTTTGAAAGAAAGGAAGAAAGAAAAAAACAA
  AGAAAAAGAATAGATTTATATGCCTATATATGACTATATGGAGTCCTGTAGATAAATACG
  AGCCCACTTTTTTTTTTCAGCCTATCCTCCCCCACAGAGGCTGCTGCGCTACTTACAAAT
  TGAATTAAATGAGGGCTGAAACGGCACGCTTCAGCATGTACTGTAGTCACCGTGGAAGAA
  CAAGTCTTTCCAATATTGGGGCATGTATTGATTTCTAAAAAATGTCTGCCTGGGGAATGA
  AATATGCACATGTATTTTATATTCACAGATCTGCTTCCGAAAACCTCTCTATTTAATATC
  ACTCAATTATGAATTTGTTTTGCTTTCAAAGGAATGGAATGCCATTTAGTTTTTATAAAT
  TTGGGGAGAGACAACACTCTGCCCCAGTTAGAGGAGAGGAAGTTCAAGGGTCCCACTGTC
  CATACTGCCGGCTAGAGGGAGATACAGAACCGGTAGAGGCCCTGGAGTGTTTTCCCCTTA
  CCTTTTTTCCCCTGACCAATCCATTCTGGGAAACCCATAAGCGCCATGATTGCCCATCCT
  GGGCTGGTTTTTTTACACTCCACTTTCCCAACCCAATACAAGCTTGACCCAAAAGTGCGC
  CCCTGTTCGCTCTGAGTCATTACCTCTTCCCACCATTTTATTACCTTTCCTCCCACTTCC
  AACATTGTCCATTTTTAATACACAG
  
• Restriction Sites: NotI-NotI
• ACCN: NM_000599
• Insert Size: 2800 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_000599.2, NP_000590.1
• RefSeq Size: 6316 bp
• RefSeq ORF: 819 bp
• Locus ID: 3488
• UniProt ID: P24593
• Cytogenetics: 2q35
• Domains: thyroglobulin_1, IB
• Protein Families: Druggable Genome, Secreted Protein
• Gene Summary: IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors.[UniProtKB/Swiss-Prot Function]