ACKR3 (NM_020311) Human Tagged ORF Clone
CXCR7 (GFP-tagged) - Human chemokine (C-X-C motif) receptor 7 (CXCR7)
|Product Name||ACKR3 (NM_020311) Human Tagged ORF Clone|
|Type||Human Tagged ORF Clone|
|Synonyms||CMKOR1; CXC-R7; CXCR-7; CXCR7; GPR159; RDC-1; RDC1|
|E. coli Selection||Ampicillin (100 ug/mL)|
>RG206092 representing NM_020311
Red=Cloning site Blue=ORF Green=Tags(s)
ACGCGTACGCGGCCGCTCGAG - GFP Tag - GTTTAA
>RG206092 representing NM_020311
Red=Cloning site Green=Tags(s)
TRTRPLE - GFP Tag - V
|Restriction Sites||SgfI-MluI Cloning Scheme for this gene Plasmid Map|
|ORF Size||1086 bp|
|OTI Disclaimer||Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at firstname.lastname@example.org or by calling 301.340.3188 option 3 for pricing and delivery.
The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
|OTI Annotation||This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.|
|Product Components||The ORF clone is ion-exchange column purified, transfection-ready dried plasmid DNA, and shipped with 2 vector sequencing primers.|
|Reconstitution||1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
|RefSeq Size||2114 bp|
|RefSeq ORF||1089 bp|
|Protein Families||Druggable Genome, GPCR, Transmembrane|
|Gene Summary||This gene encodes a member of the G-protein coupled receptor family. Although this protein was earlier thought to be a receptor for vasoactive intestinal peptide (VIP), it is now considered to be an orphan receptor, in that its endogenous ligand has not been identified. The protein is also a coreceptor for human immunodeficiency viruses (HIV). Translocations involving this gene and HMGA2 on chromosome 12 have been observed in lipomas. [provided by RefSeq, Jul 2008]|
|The use of this cDNA Clones has been cited in the following citations:|
CXCR7 expression in diffuse large B-cell lymphoma identifies a subgroup of CXCR4+ patients with good prognosis
,Moreno, MJ;Gallardo, A;Novelli, S;Mozos, A;Aragó, M;Pavón, MÁ;Céspedes, MV;Pallarès, V;Falgàs, A;Alcoceba, M;Blanco, O;Gonzalez-Díaz, M;Sierra, J;Mangues, R;Casanova, I;,
PLoS ONE 2018
,PubMed ID 29920526
|cDNA Clone Resources|
|SC112665||CXCR7 (untagged)-Human chemokine (C-X-C motif) receptor 7 (CXCR7)||
|RC206092||CXCR7 (Myc-DDK-tagged)-Human chemokine (C-X-C motif) receptor 7 (CXCR7)||
|RC206092L1||Lenti-ORF clone of CXCR7 (Myc-DDK-tagged)-Human chemokine (C-X-C motif) receptor 7 (CXCR7)||
|RC206092L2||Lenti-ORF clone of CXCR7 (mGFP-tagged)-Human chemokine (C-X-C motif) receptor 7 (CXCR7)||
|RC206092L3||Lenti-ORF clone of CXCR7 (Myc-DDK-tagged)-Human chemokine (C-X-C motif) receptor 7 (CXCR7)||
|RC206092L4||Lenti-ORF clone of CXCR7 (mGFP-tagged)-Human chemokine (C-X-C motif) receptor 7 (CXCR7)||