Zfp598 (NM_183149) Mouse Untagged Clone

CAT#: MC205568

Zfp598 (untagged) - Mouse zinc finger protein 598 (Zfp598), (10ug)

Specifications

Product Data

• Type: Mouse Untagged Clone
• Tag: Tag Free
• Symbol: Zfp598
• Synonyms: BC023040; Ntrap; Znf598
• Vector: PCMV6-Kan/Neo
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >BC050859
  CCGGCCATGGCGGCGGCGGCGGGCGCCGAGGGGCGGCGCGCGGCTCTGGAGGCGGTGGCAGCGCCGGAGC GGGGCGGCGGGAGCTGCGTGCTGTGCTGCGGTGACCTGGAGGCTACGGCGCTGGGCCGCTGCGATCACCC GGTGTGCTACCGGTGCTCTACCAAGATGCGGGTGCTGTGCGAGCAGCGCTACTGCGCCGTGTGCCGCGAG GAGCTGCGCCAGGTGGTCTTTGGGAAGAAACTCCCTGCTTTTGCCCTGATCCCCATCCATCAGCTCCAAC ACGAGAAGAAATATGACATCTATTTTGCAGATGGAAAGGTGTTTGCATTGTACAGGCAGCTGCTGCAGCA TGAGTGCCCACGGTGCCCTCACCTGCCACCCTTCAGCCTCTTCGGGGACTTGGAGCAGCACATGCGCAAG CAGCATGAGCTCTTCTGCTGCAAGTTGTGCCTCAAGCACCTCAAGATCTTCACCTATGAACGCAAGTGGT ACTCACGCAAGGACCTGGCTCGACACCGTATGCAGGGTGACCCTGATGATACATCCCATCGGGGACATCC ACTCTGTAAGTTCTGTGACGAGCGCTACCTGGACAATGACGAGCTGCTCAAGCACCTGCGCCGAGACCAC TACTTCTGCCACTTCTGTGACTCTGATGGGGCCCAGGACTACTATAGTGACTATGCCTACCTGCGTGAGC ACTTCCGGGAGAAGCACTTCCTGTGTGAGGAGGGCCGCTGCAGCACTGAGCAGTTCACCCATGCCTTCCG CACCGAGATCGACCTCAAGGCTCATAAAACAGCTTGCCACAGCCGCAGCCGGGCCGAGGCACGCCAGAAC CGGCAGATTGACCTTCAGTTTAGCTTTGCACCACGGCACTCACGCCGGAGTGAGGGAGTCGTCAGTGGTG AGGACTACGAGGAGGTGGACAGGTACAATCGCCAGGGCCGAGCTGGCCGGGCCAGCGGGCGTGGAGCCCA GCAGAACCGCCGGGGAAGCTGGAGGTACAAGAGGGAAGAAGAAGACCGAGAAGTGGCAGCTGCTATCCGG GCCTCTGTGGCTGCTCAACAGCAAGAGGAGACTCAGAGGGTTGAGGACCGGGAGGAGGGTAGCAGGCCCA AGAAAGAGGAAGCCGCAGCCAGGGTGCCTGAGGAACCCCGTGGCCACCGGCGTCTGCCTCGGGCTCAGGG TGAAGGCTCAGGCTCCAAGGAAGCCTCAGCAAATGGTCCTGTAAGCCAAGAAGCCTTCCCAGCCACAGGC CCAGGCCCAGTGGTTGCCCTCTCAAATACCCTCCCACCACCCAGCCCTGAGCTCAAGGAGGAAGACTTCC CCAGTCTCTGTGCCTCCACCTCCTCCTGCTGCACAGCGGTTACCCCAGGCTCTGTAGGCTTGGCACTGGC TTATCCTGGTCCTCCCAGGGGCAAGAACACCTTCCAGGAAGAGGACTTTCCTGCCTTGGTTTCCTCCGCA CCCAAGCCCAGCAGTGCCCCTTCCAGTCTCATCTCAGCTTGGAATAGCGGCTGCAGCAAGAAAGGGAACC TACCCACCCCGGGGTCCCAGGCTGTGGTTGGTGGCAGCCAGCCTCCCCGGAAGGCAGGAAAGGGGAGCAG GGGTGGCAGAAAGGGTGGCCCAGCCCCAGTGGATGAGGAGGATAGCGGTGGCCTCACTGTGCAGGGGCTG CGGAGTGTGCCCACCACGGTAGCTGTGTCTTCTTTGCTGGCACCAGCCACCAACCAGAGTTCAGCCAAGG TTGGCAAGAAGAAGAAGGTGGGCTCTGAGAAGCCTGGGGCCACATCATCCCCACTGTTGCCCCCTGATCA TACCCCAAAGCCCTCTGGGGCTGAGCAGGTCCTGGAAGCCCCTTTGAGCAAAGCTGAAGTGCCAGTAACC ATCGTTGTCAATGGACATTCCGAAGGGTCAGCCCTGGTACGGAGTGCCCCAAAGGAACCTCCAGGGCTTC CAAGGCCCCTCGGTCCCCTCCCCTGCCCCATACCACAGGAGGACTTTCCAGCTCTCGGAGGCCCTTGTCC ACCCAGGATGCCTCCTCCCCCAGGCTTCAGCACCGTGGTACTCTTGAAGGGCACACCACCTCCACCCCCA CCCCCACCCGGCCTGGTGCCTCCCATCAGCAAGCCACCCCCTGGCTTCTCTAGTCTTCTGCCCAGCTCCC ACTCAGCCTGTGCTCCTAGTCCCACCACCACAACCACCACCACCACCACCACGAAAACACCCGGGCTAGC ACCCACACCACAAGCCTACTTAGTTCCTGAGAATTTCCGGGAGAGAAACCTGCAGCTTATCCAGTCTATC AAGGACTTTCTGCAAAGCGATGAGGCCTGCTTCAGCAAGTTTAAAAGCCATTCGGGGGAGTTCAGACAGG GGATGATCTCTGCGGCTCAGTACTACAAGAGCTGCAGGGACCTGCTTGGAGAGAGCTTCCAGAAGATCTT CAGTGAGCTGCTGGCGCTCCTGCCAGACACAGCCAAACAGCAGGAGCTGCTGTCTGCACACACAGACTTC TGCAGTCGTGAGAAGCCTCCCAACTCCAGATCTAAGAGGAACAAGAAGAATGTGTGGCAGACCAGCACCC AACAGTTGGGCCTGGACTGCTGTGTGTGCCCCACCTGCCAGCAGGTACTGGCACACGGTGACGTCAGCAG CCACCAGGCACTGCACGCTGCCCGGGACGATGACTTCCCCTCCCTTCAAGCCATTGCCAGGATCATTACG TAGCTGCTGCTGGTGAGGGCAGGAGCTGTCACACCCTAGCGCCTCCTTTCTCCTTCCTCCCTCTTCCCAG CTGCTTGGCCCTGGTAGGGCCCTGGGAAGGCCGAAGGCCAGGCCTCCTGGTTAGCCAGGCCTGCCAGGTG GACATCAGGAAAGGTCTACCCTGTGCACCGTCACTCATAAGTTCTGTCCCATGCTTGGCTGAGGGTCAGT CTTGGTTTGTGATCTTGTGATTTTGGAATGTGCCAGGGGAGGGAAAGGCTAGGATGCTGGGACCTGAGCT AGAGGCCTCAGTGGCCTGAAGAGAGTTCTCGTGAGGCAAGTCCATAGCCCCAGAGCTGACAGCTTCGGGT CCACTGGTGCTGGAGTCAGATGTCAAGTGTGTTGTGTAAACAATTGGCTGTTTCATAGAGAATGTTCCAG ATTAAAAACAGACACAAAATTGTGCTACTTGAAGTTCAATCTTTTTACAAGACAAGTTAAATCTAAGATC TCAAATTGCCTCTGACATTTTATAAAAGACAGTTTATCTTCAAATAAATTTATTTTGCAGTACTGCAAAA AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
• Restriction Sites: RsrII-NotI
• ACCN: NM_183149
• Insert Size: 2727 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: BC050859, AAH50859
• RefSeq Size: 3323 bp
• RefSeq ORF: 2727 bp
• Locus ID: 213753
• UniProt ID: Q80YR4
• Cytogenetics: 17 A3.3
• Gene Summary: E3 ubiquitin-protein ligase that plays a key role in the ribosome quality control (RQC), a pathway that takes place when a ribosome has stalled during translation. Required for ribosomes to terminally stall during translation of poly(A) sequences by mediating monoubiquitination of 40S ribosomal protein RPS10/eS10, RPS20/uS10 and RPS3/uS3. Stalling precludes synthesis of a long poly-lysine tail and initiates the RQC pathway to degrade the potentially detrimental aberrant nascent polypeptide. Also acts as a component of the 4EHP-GYF2 complex, a multiprotein complex that acts as a repressor of translation initiation.[UniProtKB/Swiss-Prot Function]
  Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1). COMPLETENESS: complete on the 3' end.