Fkbp8 (NM_001111066) Mouse Untagged Clone

CAT#: MC205390

Fkbp8 (untagged) - Mouse FK506 binding protein 8 (Fkbp8), transcript variant 1, (10ug)

Specifications

Product Data

• Type: Mouse Untagged Clone
• Tag: Tag Free
• Symbol: Fkbp8
• Synonyms: 38kDa; FKBP-8; FKBP-38; Fkbp38
• Vector: PCMV6-Kan/Neo
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >BC027808
  CCCACGCGTCCGACAGGACCCCGAGCGGGGTCCCCGAGCCGCAGGGCCAGTTCCTGATCCCAGCAGCATG GCGTCTTGGGCTGAGCCCTCTGAGCCTGCTGCCCTGCGACTTCCTGGGGCCCCACTGCTGGAGGGCTTTG AGGTGCTCGATGGGGTTGATGATGCAGAGGAGGAAGATGACCTAAGTGGGCTGCCACCACTAGAGGACAT GGGACAGCCTACAGTGGAGGAGGCTGAGCAGCCTGGAGCCCTGGCTCGGGAGTTCCTGGCAGCCACAGAG CCTGAGCCAGCCCCAGCCCCAGCCCCGGAAGAGTGGCTGGACATTCTGGGGAACGGATTGCTGCGGATGA AGACACTGGTCCCAGGCCCGAAAGGCTCTAGCCGCCCACTCAAGGGCCAGGTGGTGACCGTTCACCTGCA GATGTCCCTGGAGAATGGCACCCGCGTACAGGAAGAGCCTGAACTGGCCTTCACGCTGGGAGACTGCGAT GTTATCCAGGCCCTGGACCTCAGTGTCCCGCTCATGGATGTGGGCGAGACAGCCATGGTTACCGCTGACT CCAAGTACTGCTACGGCCCCCAGGGCAGCAGGAGCCCATACATCCCCCCCCACGCAGCCCTGTGCCTGGA AGTCACCCTGAAGACGGCAGAGGATGGACCCGACCTGGAGATGCTGAGTGGGCAGGAGCGCGTGGCCCTG GCCAACCGCAAGCGGGAGTGTGGCAATGCCCACTACCAGCGTGCTGACTTTGTGCTGGCCGCCAATTCCT ATGACCTGGCCATCAAGGCTATCACCTCCAACACCAAAGTGGACATGACTTGTGAGGAGGAAGAGGAGCT GCTACAGCTGAAGGTCAAGTGTCTGAACAACCTTGCGGCCTCACAGCTGAAGCTGGACCACTACCGAGCA GCTCTGCGCTCCTGTAGCCAGGTGCTGGAGCACCAGCCGGACAACATCAAGGCACTGTTCCGCAAGGGCA AGGTGCTGGCTCAGCAAGGTGAATATAGTGAGGCCATCCCAATCCTGAGGGCTGCCCTGAAGCTGGAACC TTCCAACAAGACGATCCACGCAGAGCTCTCAAAGCTGGTAAAGAAGCGTGCTGCACAGCGGAGCACAGAG ACCGCCCTGTACCGAAAGATGCTAGGCAACCCCAGCCGGCTGCCTGCCAAGTGTCCGGGAAAGGGGGCCT GGTCCATCCCGTGGAAATGGCTGTTTGGGGCGACTGCCGTGGCCCTGGGGGGCGTGGCTCTCTCTGTGGT CATTGCTGCCAGGAACTGACTGTCCCCCTGCTCACCTGGACCCCAACCTGTGCTCCCTAACTCCCCCAGG CTCCCTGTCCATTGCCCTCCCTGGCTGAGATGCCTCCTATGGGTTTGGGGAGCAAGGATTGAGGGTCAAA TAACCCAAGAAGCAGGAAGGACTGAGACCCTGAGGGGGGACATGGGGTGCAGCCCAGAGGGAGGGACCCT GTTCTTCTAGACCCAGTTGTTTCTATCCCACAACCCTGTCCTCTGGGGTCAGGCCTCGGCTGTGACAGCC TCAGTTTTCCCTCTCAGTAGGCCTGGGGCAGCACTACCATTCCTTCCTGCCCGTCTGCACCCTCTGTCCA GGCTTCCCCACAGTGAATTAAATAAAGCCTCACCCCACACCCTAAAAAAAAAAAAAAAAAAAAAAA
• Restriction Sites: RsrII-NotI
• ACCN: NM_001111066
• Insert Size: 1212 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_001111066.1, NP_001104536.1
• RefSeq Size: 1730 bp
• RefSeq ORF: 1212 bp
• Locus ID: 14232
• UniProt ID: O35465
• Cytogenetics: 8 B3.3
• Gene Summary: Constitutively inactive PPiase, which becomes active when bound to calmodulin and calcium. Seems to act as a chaperone for BCL2, targets it to the mitochondria and modulates its phosphorylation state. The BCL2/FKBP8/calmodulin/calcium complex probably interferes with the binding of BCL2 to its targets. The active form of FKBP8 may therefore play a role in the regulation of apoptosis (By similarity). Required for normal embryonic development.[UniProtKB/Swiss-Prot Function]
  Transcript Variant: This variant (1) encodes the longer protein (isoform a). Variants 1 and 3 encode the same protein.