Kdm4c (NM_144787) Mouse Untagged Clone

CAT#: MC203967

Kdm4c (untagged) - Mouse lysine (K)-specific demethylase 4C (Kdm4c), transcript variant 1, (10ug)

Specifications

Product Data

• Type: Mouse Untagged Clone
• Tag: Tag Free
• Symbol: Kdm4c
• Synonyms: 2410141F18Rik; AA517467; Gasc1; Jmjd2c
• Vector: PCMV6-Kan/Neo
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >BC020180
  CCCACGCGTCCGCGCCCCGTGCGCGTGCGCAGCGAACAGCTGTCACCCAGTGCGGAACAAGTCTTCCAAA GATTCCCAAAACCCTCAGGGGAGGCCGCACTTTTCATCCCTTTCATTCGGGTGGCGTCTGGACCTCCGCC AGCGGCGCAGAAACATCTGTGGCCATCATGGAGGTGGTGGAGGTGGAGAGTCCCCTAAATCCCAGCTGTA AGATAATGACCTTCAGACCTTCCATGGAGGAGTTTCGGGAGTTCAACAAATACCTCGCATACATGGAATC CAAAGGAGCCCATCGAGCAGGTCTTGCCAAGGTGATTCCTCCTAAGGAGTGGAAGCCAAGACAGTGCTAT GATGATATTGATAATTTGCTCATCCCAGCACCAATTCAGCAGATGGTCACAGGGCAGTCGGGACTGTTCA CGCAATACAACATCCAGAAGAAAGCCATGACTGTGAAGGAGTTCAGGCAGCTGGCTAACAGCAGCAAATA CTGTACTCCAAGATACTTGGATTATGAAGATTTGGAACGCAAATACTGGAAAAACTTAACTTTTGTGGCA CCTATTTATGGAGCAGATATAAATGGGAGCATTTATGATGAGGGTGTGGATGAATGGAATATAGCTCGCC TAAATACAGTCTTGGATGTGGTTGAAGAAGAGTGTGGTATTTCTATTGAGGGGGTAAATACCCCTTATCT CTATTTTGGAATGTGGAAAACAACATTTGCGTGGCACACGGAGGACATGGATCTCTACAGTATTAATTAT CTCCACTTTGGGGAGCCCAAGTCTTGGTATGCTATACCTCCGGAGCATGGAAAGCGACTTGAAAGACTAG CCCAAGGCTTCTTCCCCAGTAGCTCCCAAGGCTGTGATGCATTTCTCCGGCACAAGATGACCCTCATTTC CCCCTCAGTGCTGAAGAAGTATGGCATTCCCTTCGACAAGATCACCCAGGAGGCTGGAGAGTTTATGATC ACTTTTCCTTATGGATATCATGCTGGTTTTAATCATGGTTTCAATTGTGCTGAGTCTACAAATTTTGCTA CAGTCAGATGGATTGACTACGGCAAGGTTGCTAAGTTGTGCACTTGTCGGAATGACATGGTGAAGATATC AATGGATATATTTGTGAAGAAATTTCAGCCAGATAGATACCAGATTTGGAAACAAGGAAAGGATATATAT ACTATTGACCATACAAAGCCCACTCCAGAATCTACTCCAGAAGTAAAAACATGGCTACAGAGGAAGAAAA AATTAAGAAAGCCTCCCAAGAGCTTACAGGGCAATAAGCCACTTTGTAAAAGGCCTAAACCTGAAGAAGA TGAGGAATTTGCTGAATTTAGTGGGGAAGAGGGTGCAAACCCTGCCATGGGCCCTAGGCACCTCAAAGTC ACTGAAAAGCCAGAAAAAGCATTAAAGCTGGGGAAATTAGAAGAATCTTCAGCAAAAGAAGCTTTGGATA CCAGGATACAGGTGGATCAAAGCTTACTGAACGACACCAAGCTCTCGGGAAAAGGTTGCATAAGTTCATC AGTAACAGCTGAAATTCCACCAGAAGACAACAGAGCCAGTGCTGTAATTTCACCATCTCAGCTGAAGGAG GGCGCTGACTGCATACCACTTTCTCATGGCCATCAAGCAGGCAAAGAGTCACATCTACTTAAGATTCTAA AGCTTGAATCTCCCAAGATACCTTCCCCCCTGCCAGAAAGTAATAAAGTATTGACAGAGGGAGAAGAAAA TGATGAAGAGGGCCATGGAAGTAACCTTGAGCCTGGGGAAATCCCAGAAGCTCTTAGTGAAGAGAGAAAT GGGCTCAACATTCCTAAGATAATTGAAGGACAGCCAAAAACTACTAAGAGTTGGCGCCATCCACTTGGTA AGCCTCCGGCCAGATCCCCAATGACACTTGTGAAGCAGCAGGTAGCGAGTGATGAAGAATTGCCTGAGGT TCTAAGCATTGACGAAGAAGTTGAAGAAACAGAGTCTTGGGCAAAGCCTCTCATCCACCTTTGGCAGACA AAGTCTCCTAACTTTATGGCTGAACAGGAGTACAATGCAACTGTTGCAAAAATGGAGCCAAACTGTGCCA TCTGCACTCTGCTCATGCCGTACTACAAGCCTGATAGCAGCAAAGAAGAAAATGATTCTAGATGGGAGAC AGCAGTAAATGAAGTGGTTCAATCTGGAAGAAAGACTAAGCCCATTATTCCAGAGATGTGTTTTATTTAT AGTGAAGAAAATGTAGACTATTCCCCCCCAAATGCCTTCCTTGAAGAAGATGGAACAAGTCTTCTGATTT CCTGTGCCAAGTGCTTCGTGCGGGTTCATGCAAGTTGTTATGGTGTCCCTTCTCATGAAGTCTGTGATGG ATGGCTGTGTGCCCGGTGCAAGAGAAATGCATGGACTGCAGAATGCTGTCTCTGCAATTTGAGGGGAGGT GCTCTGAAACAGACTAAGAACAATCAGTGGGCTCATGTCATATGTGCTGTTGCAGTTCCAGAAGTGCGAT TCACTAATGTCCCAGAACGGACACAAATAGATGTAGACAGAATACCTTTACAGAGGTTAAAATTGAAATG CATCTTCTGTAGACACCGGGTTAAAAAGGTTTCTGGAGCCTGCATCCAGTGTTCTTATGGCCGCTGCCCA GCTTCATTCCATGTTACGTGTGCCCATGCTGCTGGAGTGCTCATGGAGCCTGATGACTGGCCTTACGTGG TAAACATCACATGCTTCAGACATAGAGTCAACTCAAACGCGAAATCCAAAACTTGTGAGAAAGCCATTTC TGTGGGTCAGACAGTCATCACAAAACATCGAAACACTCGGTACTACAGCTGCAGAGTGATAGATGTGACA TCTCAAACCTTCTATGAGGTCATGTTTGATGATGGCTCCTTCAGCAGAGACACATTTCCTGAAGATATTG TGAGCCGAAACTGTGTGAAGCTGGGCCCTCCTGCGGAGGGAGAAGTCATCCAAGTCAAATGGCCTGATGG TAAACTCTATGGGGCAAAGTATCTTGGATCAAATGTTGCCTATATGTATCAGGTTGAATTTGAAGATGGA TCGCAGATTGCAATGAAGAGAGAAGACATATACACTTTAGATGAAGAGTTACCCAAGAGAGTAAAGGCTC GTTTTTCCACAGCCTCCGACATGCGATTTGAAGACACATTTTATGGAGCAGATGTAATCCAAGGGGAGAG GAAGAGGCAAAGAGTGCTAAGCTCCAGGCTCAAGAATGAGTATGTGGATGACCCTGTGTATCGTACTTTC CTGAAGAGTTCTTTCCAGAAGAAGTGTCAGAAGAGACAGTAGTTGATAATGTGCAGCAGCCACAGTGCAG CTCAGACCAGAAGAGGGAAGACAAAGGGACAGCCTTGGGGTACACATTGGGACAGGTGGCTGGGTGCTTC TTTGGTATTGGTAATAAACCAGGCTTCTGGAGTTTGATTACCAAGCAACCAAGAAGAGACATATTAGTTG CTTCTGTAATCTGATCACCCCTCAGTCATTTGTTTGACCCCAAAGAATATTCCTAAATTAAAGGAAACAG CAGTGAATGGCCCACTAGATAAAACAACTGCTAAAGAAGCGGGGTTCCCTCTCTGGCTCAGGTCCCTTCC TCAGGGAACACATTTGGAGGCTCCTTTCCCACCTCCTTCAGTGGCAGCCTCATCACCCAACAGCCGGTGG GTGTATTTATATATATTTTCCACAGCCAGGGAAAGAGTCTCACTCACATTTGTTTTCAGTGGCAGTTTTT ATAAAACATTTTTAAAACACAAATGGCATGTATGGTAATAGGATTTACCTGTATGCTATCTTCCCTTGTA CAGAACTTTTCCATTTTTTATATTATTACTTTTGATTGTGTCTGAAAACTGAGTTGGCCTTTATAAGAGG AAATTTTTTGCTCTTGAAGAGGAATTCATATGAAGTATATGGGAATTTTATATATTTACAGAGGAAAAAT CTTGGCCTGATATTTTGAACACTTCATAATTCCTGTTCTGAAATGATATTTATAAAATATATATTTCTTT CATTATGTGTTTGTAAAAATTAGAGTTTAAAGAAATATACTTAATGCATAGTTTTAAACTAATGTAACAT GATTTTTCTTTGCAAAACAGCCTGGAGATGTATTAATATTTAAAAATTAAAATCTGTTTTCTCCTGAAAA AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
• Restriction Sites: RsrII-NotI
• ACCN: NM_144787
• Insert Size: 3165 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: BC020180, AAH20180
• RefSeq Size: 4231 bp
• RefSeq ORF: 3165 bp
• Locus ID: 76804
• UniProt ID: Q8VCD7
• Cytogenetics: 4 C3
• Gene Summary: Histone demethylase that specifically demethylates 'Lys-9' and 'Lys-36' residues of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 'Lys-4', H3 'Lys-27' nor H4 'Lys-20'. Demethylates trimethylated H3 'Lys-9' and H3 'Lys-36' residue, while it has no activity on mono- and dimethylated residues. Demethylation of Lys residue generates formaldehyde and succinate (By similarity).[UniProtKB/Swiss-Prot Function]
  Transcript Variant: This variant (1) represents the longer transcript but encodes the shorter isoform (1).