Lgi1 (NM_020278) Mouse Untagged Clone

CAT#: MC203484

Lgi1 (untagged) - Mouse leucine-rich repeat LGI family, member 1 (Lgi1), (10ug)

Specifications

Product Data

• Type: Mouse Untagged Clone
• Tag: Tag Free
• Symbol: Lgi1
• Synonyms: BB130740
• Vector: PCMV6-Kan/Neo
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >BC066090
  CAGAGAAGGGTGGACTCCTATGTGACCTGTTCTTAGAGCAAGACAATCAGCAGCTGAATTCCAGAAGCCC TGTTCATGTGTGGGGATATTCTCTCGACTGCATGGAATCAGAAAGCAGCAGAAGGATGGGAAATGCCTGC ATTCCCCTGAAAAGAATTGCCTATTTCCTATGCCTCTTTTCTGTGGTTTTGCTGACTGAGGGGAAGAAAC CAGCGAAGCCAAAATGCCCTGCCGTGTGTACTTGTAGCAAAGATAACGCTTTATGTGAGAATGCGAGATC CATTCCACGCACCGTTCCTCCTGATGTTATCTCACTATCCTTTGTGAGATCTGGTTTTACTGAAATCTCA GAAGGGAGTTTCTTATTCACACCATCGCTGCAGCTCTTGTTATTTACGTCGAACTCCTTTGATGTGATCA GTGATGATGCTTTTATTGGTCTTCCACATCTAGAATATTTATTCATAGAAAACAACAATATCAAGTCCAT TTCAAGACATACTTTCCGGGGACTCAAGTCTTTGATTCACTTGAGTCTTGCAAACAACAATCTCCAGACA CTCCCAAAAGACATTTTCAAAGGCCTGGATTCCTTAACAAATGTGGACCTAAGAGGGAACGCATTTAATT GTGACTGTAAGTTGAAGTGGCTGGTGGAATGGCTCGGCCATACCAATGCAACTGTGGAAGACATCTACTG TGAAGGCCCACCGGAATATAAGAAACGGAAAATCAATAGCCTCTCCCCCAAGGATTTTGACTGTATCATT ACAGAATTTGCAAAGTCCCAAGACCTACCTTATCAGTCGCTGTCCATAGACACTTTTTCTTATTTGAATG ATGAATATGTAGTCATTGCTCAGCCTTTTACTGGAAAATGCATTTTCCTGGAATGGGACCACGTAGAGAA GACCTTCCGGAATTATGACAACATTACAGGCACGTCCACTGTGGTGTGCAAGCCCATAGTTATTGACACT CAGCTCTATGTCATTGTGGCCCAGCTGTTTGGTGGCTCTCATATCTATAAGCGAGATGGTTTTGCAAACA AATTCATAAAAATCCAAGATATTGAAGTTCTCAAAATTCGAAAACCCAATGACATCGAAACATTCAAGAT TGAAGACAACTGGTACTTCGTTGTCGCTGACAGTTCCAAAGCTGGGTTTACTACCATTTACAAGTGGAAT GGAAACGGATTCTACTCCCACCAATCCTTACATGCCTGGTACAGGGATACTGATGTGGAATACCTTGAAA TAGCCAGACCACCATTGGCCCTCAGAACACCTCATTTAATCCTGTCCAGTAGTTCTCAGCGCCCTGTTAT TTACCAGTGGAGCAAAGCAACACAGCTATTCACTAACCAAACCGACATTCCTAACATGGAGGACGTATAC GCGGTGAAGCACTTCTCTGTGAAAGGTGATGTGTACATCTGCTTGACCAGATTCATTGGCGACTCTAAAG TCATGAAGTGGGGCGGCTCCTCCTTCCAGGACATCCAGAGGATGCCATCTCGAGGATCCATGGTGTTCCA ACCTCTTCAGATAAATAATTACCAATATGCAATTCTCGGAAGCGATTACTCCTTTACTCAAGTGTATAAC TGGGATGCAGAGAAAGCCAAATTTGTGAAGTTTCAGGAGTTAAACGTTCAGGCACCCAGATCATTCACAC ACGTATCCATTAATAAGCGTAATTTTCTCTTTGCTTCCAGTTTTAAGGGAAACACGCAGATTTACAAACA TGTCATAGTTGACTTAAGCGCATGAGACACCAAACTCCACGGCTGCCATCGGAAACTTTCTACAGTGCGT GACCTGGATGAACTCAATGCATGATGACTCTTCTTATCACACTTGCAGATGAATACCTTTCAACACTGAG ACTGCTAAAGCCAATACTACCAGTATCACCATCCTTAACTGTCCGGTCCAGTGGTGTGGGAAGTTACCTT TTATAAGACAAAAGTTTCCTTATGTAACTGTTCTTTGCAGTGAAGATGTGTAAATAAGCGTTTAATGGCA TCTGTTACTCCGAAAAGAAATATTCATATGTACTTTTCCATTTATTTATTCACGTGTTCAGAAACAACTG CCAAATAAAATGTTTACATTTTCTTTCATATCCCAAAGGTAATTATTTACAAGAGCTGTTTGATTCCTGT TGATTGTATGTTGAGGAAATAGTTTTATACACTAGGATTATATTTGGATCAAGGATTTATTGTATGAATA TTGAGTAAAGATAACAAATGAAAATAATTTCCCATAATTTATAAGCACCTTTATCCGGGTTCTATCCGTG GGTTTTGAATACTCAGAAGTCACGACGTTTAGGGACACTTAAAGGTGAAAGGGTAACACCCTTCAATGAG AGGGAGTTTGCCTATTATGATAAGGCTAACCTGTAATGAGAAGGAAGACCACCCTGTTCTATCTGATAGC CTGGGTTAAATACCACTCAGCCATTTTATAGAAGAAATTTCAGATTTAGGATTGAAAAGCTCCTGATCTG GGACCTTCTGAATATCTAACTCTAGAGTCTCCTGACAGCTGGTAGATTGTAAATTATGGAGAGCACTTGC CTCCCAACATGCTGGCCCTGGAGGCCTCTCTATCTGGCAGAGGACATTTTGCTTCTAGACACTGGATTTG CTGTGACTGACCTGCCACACAGTGCCTGTGAGGCTCATGTTTGATTTTCTAGATTCCTGCTTCTGGATCA CTTGAGTCATTAGTAGCTAGCACAATGCCTGTTATGTACATGTAGGCTCTCAAACATTGCTTTTCAAAGG CTGAGGATATAGTTTCACGGAAAAGTACTCAATGTGGCCTGTGTAAAACCTGGAGTTCAATTCCCAGCAT AAAACAAAAGAGTTTGCGGGGGTGGAGGGGGAACGAGTGACTCCTTCTCTTATAATAAACTCCACGGGTC CCTCTGACCTATCGAGTACTTACTGGCTACTTGTTCAGAATATGGTGTGGTTGTGGGTAACTAATACAGG AGGAGGGTGCAATGCTCACCCTCTGTAGTCTTGAAAAAGATTGGCAGCGGGCTAAATATACAAAAACATC TATAGATTAAGCAATGTGTACAAAGAATGACCTGAAAATTCTAGATTTTGAGTATCATGGGAACAACCAG AGCAACTTTGGGGAAGCTATGCTCTTCGTCTGACTTAAAGGGAAGAGGCAAAAGAAAGTGTGTAGGGAAG ACATTGCGGGCACAAACTGGTTATGTGTGCTGCCTCTATGGAGAGCTTTTGAGCTTGCTATGTTCCCACT GGATGGAGGTAGGCAGACAGCAGTACCCTCTGCCCAGGATAAGTCTGGTTGCCTGGAGCATCAGGGGTCT CCACAATAATCACACAGTCTCCAAAGAAGCAACACCCTGGGTCACCACGCACAAAGACAGAATTTCATTA CTCATCTAGAAAAGATAGTAGATTTGGCTTCAGAGTGATAAGGAAGAGGAAAGCTTAACTCCTGATCATT CGCTGGCCTTGGAATGCCTTTTCCTTTGTTCTAATAAGCAACATCATCATATGCTGCTGGAGGACGCCTG CACTGTACAGTCGGAGTTGAAATCTAGCTCTGCCATGCACAGGCTTTGTAACAGGAAAGATCTTAACCAA CCTGAGCCCACTTCTTCATTCGTAAAGATGGATAACAAAACCTACTTCTGAGAAGAGGGATAAATGAGAA AACCCGTGAACAGCAGATGGTATTTTTTCCAAATACATCCCCTACCGCACCTTGAACCCCCACGCCTGTG AGACCTTGTCCAAAATTCACTAAGAGGTAGCATCGAACTCACCTGAATGGTTGGTGACTTGCTGTTAATA CGTTGAATTTGGTGAAAGTGATAGTTTGGCTTCCACGCTAAGTCATAAAAACCATGAACTCCTTCTTGCC TTGCAAATTGGAACACTTGCCTGCAGAGCCCAGAACATCTGCATAAGAAGTCTTTCTAACCAGAGGCCAT TCTTCTTTGTTGAAAACCAATCCCCTCGGGAGCAACCACCTCCTGGTGCTCTGGTCAACAGGCCCAGCTG GTGTTGCAGCCAACAGCCATCATCAACCACCAGTCCTGTAAAGCCTACAGCTCCAGACCGTGTGGTCAAG TTCCTACCAGACATCAGACCTTCCCACCTAAGGGGCAGCCATTAAAGAGCAGCAAGCCATCCACAATATC CCTGCCCAAATTTGTGACCCGGACTCTATGAGAATAATAAAGTGGTTGTTTTAAATGGAAAAAAAAAAAA AAAAAAAAAAAAAAA
• Restriction Sites: AscI-NotI
• ACCN: NM_020278
• Insert Size: 1674 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: BC066090, AAH66090
• RefSeq Size: 4285 bp
• RefSeq ORF: 1674 bp
• Locus ID: 56839
• UniProt ID: Q9JIA1
• Cytogenetics: 19 C3
• Gene Summary: Regulates voltage-gated potassium channels assembled from KCNA1, KCNA4 and KCNAB1. It slows down channel inactivation by precluding channel closure mediated by the KCNAB1 subunit. Ligand for ADAM22 that positively regulates synaptic transmission mediated by AMPA-type glutamate receptors. Plays a role in suppressing the production of MMP1/3 through the phosphatidylinositol 3-kinase/ERK pathway (By similarity).[UniProtKB/Swiss-Prot Function]