Cisd2 (NM_025902) Mouse Untagged Clone

CAT#: MC203342

Cisd2 (untagged) - Mouse CDGSH iron sulfur domain 2 (Cisd2), (10ug)

Specifications

Product Data

• Type: Mouse Untagged Clone
• Tag: Tag Free
• Symbol: Cisd2
• Synonyms: 1500009M05Rik; 1500026J14Rik; 1500031D15Rik; AI848398; B630006A20Rik; Miner1; Noxp70
• Vector: PCMV6-Kan/Neo
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >BC058279
  CCGCGAGCCCGCCGGCCGCTTCCGCTCTCACGCAAGCGCAGCAGCCGGGCAGCGGACGCCGCCGGCGGCA GGATGGTCCTGGACAGCGTGGCCCGCATCGTGAAGGTGCAGCTGCCCGCCTACCTCAAGCAGCTCCCGGT CCCCGACAGCATCACCGGGTTCGCCCGCCTCACAGTTTCAGACTGGCTCCGCCTACTGCCCTTCCTCGGG GTACTTGCGCTTCTGGGCTACCTCGCAGTGCGCCCATTCTTCCCAAAGAAGAAGCAACAGAAGGATAGCT TGATCAATCTTAAGATACAAAAGGAAAATCCCAAGGTGGTGAATGAGATAAACATTGAAGATCTGTGTCT CACCAAAGCAGCTTATTGTAGGTGCTGGCGGTCCAAGACGTTTCCTGCCTGTGATGGATCCCATAATAAG CATAATGAATTGACAGGCGATAACGTGGGTCCTCTCATCCTGAAGAAGAAAGAAGTATAGCAGTGGCCAT TTGAGATGAAACTCTGACAGAGTGTTTCCATGTGTGTTGTGCATAGAAAAGTCTTTGGAAGTTTTAACTC TCAGTACTGGTTGAATAATTATTTCTGCCAGTTATTTTCTTGCTACACTACTGCTTATATTTGGTACTTT ATATAGTCAGTCATTTCTATAGAAATCAGATGGTCAAGTCTCATTCTGAAATTAAGTTTAATGTGTCTTT CAACAATAAAGTCAGCACTTCAGATTTTAATTAATTGGGAATTTAAAGTTTGACTGTGGGCCAAAAGTTA TTTCTTTGTATATCAGTATTTCAACAGAATACATAGTTTTAAAAAAATTATCCTTTGTTCTGTTAAATGT ATCTTTATATTGTCTTGTTTTGCTCATTTGAAGTCATTTGCCATTTTTTTGGCCTTTTGTGGAACTCTGC TGCTTTTAGAAGAATTATGAAAAATAATTGCCATCAACAATATTTTGAGGCAGTAAAACCCCTTGTTTTA TAGAGACTTTCATCTTATTACCATGATTATCCCAATTTCTAAAAAGTAAATCAGATATAAAAATTTCCAA TTAGAAACAATTATTTTCATCATAAAAATGGTTCACCTTACAAAAGCCTTGTTGTGTGTGTGAGGGTGTG AGGGTGTATATGTGTGTGTGAGTATGTGTGTGTGTGTGAGAGAGAGAGAGTATGTGTGTGTGTGTGTGGT GCTTAACTTGGAGACTGCTGGGTGGCAAGAGCACTCATGAACTAGAGTTTGAAGATCAGTTAGATATTAA ATAACTGAATTTGCATTAAAATGATGCATAGTTCATTGCTCAAAATTATGTTTTATCTTTTCTGTTGTAA ATTATAGAGAAACGGCAACAGGATATTAAGTTCTTGTATTCTAATGGATTGAATTTGTACATACTGAGAG AAAATATTTTGATCTTTTTTAAAAGAGATAACTCTTGTTGTATTTTTTTAACGTCACAAAATATAGATCA AACACTTGTGGGCATAATGACAGAAAAAAAGTCTGGAAGGACCAAGGACTATGACTATGACACAGCATGG TCCACTTGCACGGATAAGGACGAGGACTTAGCAAAGGTTGCTGCTTTTACTCTCTATTTCTCTTCCCCCC CCCCCCCCCCGCAACAAACCTTTATATGCTTTGCTTTTAATTGATCTTTTCTTAATTGAGGCTTTGAATA GAATCGTCATAGCACAGTTAAGCTCTTTAGGCCCGAGTGATAAGACCTGATTGATTGTCTAAGGATAGGG TGGAGCCAGCAGGGCAGGAAGCATCATCACAAGTGGATTAGACAGAGGCTGTTCGAGGAGAGGAAGCCAC ACACGTGTTACAGCAAATACTGAAAAAACCAAAACACCAACAGTCCTTTCACGTCTGGCTCCTAAGTGAA ATGACACGTCAAGGGCAAGGTAGGCTAAATAAAGAAGGTGGGCTTTAAGTATGTACTTCAGTTCTGCCGT GTTCCCCCAGAAGCAGGGTAAAAGCAAGACAGTTAAATCTGGGGACACTCACCTGTCTGCCTGCTGGAGT AGATGGACCATCTCTAGGATTTCTTCTTTATTAAATGAGCACACAGTATGCCTGGTACCACATGAATTCT GTTTGTTCTCTTTCTTTAGCTATCCTATCTAGCAGTTTGAGAAAGACTAGTGATGGCAAGCTAAAAAGGA AAATGATTACCAGTCAACTTGTCACAAAATTAAGTTACACTGACACAGTTTGTAGTCTTAGTTTGTGTAT TGTAAAGTGTAAATAATGTTAAAACAGACAGACATGTTTTAGAAAGACTTATTTCATGTGTATGAGTGCC TGTCTGCCTGTCTGTGTGTCTGTCTGTGCACCATGCACATGCCTGGTGCCCGAGGAAGCCAGAGAGAATG TTGGATCCCTGGAACTGGAATTAACAGATAGTTGTGAGCTACCATGTGAATACTGGGAACTGAACCTGGT CTCCTACAAGAACATCCAGTGCTATTAACAACTGAGCCATCTCTCTAACCCTATAAAACTTTTAATAAAA GAGGTTATGATTGGTTTGAAGTAGCAACTGAAATGTGGAAGGAAGTATTCCGAAAGGCAGAAGTGGTACA AAGCCGTGTCTGCTCACTCCACTCATGGTACTGAGGATGGAACCCAGGGCCTCCCACACCCTGGCAAGAG CCCTTCACACTGAGCTCCGTCTTGAGTTGTATCTTTTCAATAGCATAAACCATTGAGACAAAATACAAGA AAGTTTTCCATATAGGTTTACTGGAATTTTTGAATTATTTGTGATTTTAGCCTACTATCAGAAGTCTCTT TAGTTTTATTTTACAAGTCTCATGTAAGAGCTATTCTTAAACTATTAAAGATACAACCTACTCGTTAAAA AAAAAAAAAAA
• Restriction Sites: RsrII-NotI
• ACCN: NM_025902
• Insert Size: 408 bp
• OTI Disclaimer: Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.
  
  The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: BC058279, AAH58279
• RefSeq Size: 2881 bp
• RefSeq ORF: 408 bp
• Locus ID: 67006
• UniProt ID: Q9CQB5
• Cytogenetics: 3 G3
• Gene Summary: Regulator of autophagy that contributes to antagonize BECN1-mediated cellular autophagy at the endoplasmic reticulum. Participates in the interaction of BCL2 with BECN1 and is required for BCL2-mediated depression of endoplasmic reticulum Ca(2+) stores during autophagy. Contributes to BIK-initiated autophagy, while it is not involved in BIK-dependent activation of caspases. Involved in life span control, probably via its function as regulator of autophagy (By similarity).[UniProtKB/Swiss-Prot Function]