Rgs8 (NM_026380) Mouse Untagged Clone

CAT#: MC202497

Rgs8 (untagged) - Mouse regulator of G-protein signaling 8 (Rgs8), (10ug)

Specifications

Product Data

• Type: Mouse Untagged Clone
• Tag: Tag Free
• Symbol: Rgs8
• Synonyms: 6530413N01Rik
• Vector: PCMV6-Kan/Neo
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >BC065056 sequence for NM_026380
  CCGCTCCCTCCCCTGCGCTCGCTAGCTCTTTCCCTTTTCATGAGATGCAAAGTCCGGCGCAGAGCAGAGC CCTCCAGAGCAGCATGGTGCAGGAGCTCTTCTAGGGGCCCGAGGTGAGGCGGCCACGCTCCACTACCCTC ACCCATGTACCAGGAGAGGGCCGACTCTGTCACTCAGGGTTTCACCGAGCCATGCACTGCTGTTGCCGGC ACCAGCCACATCTTTCCAGCTGCGCTGCCCACCGCCAGGCAGAGCTCCTTAACCCGGAGGAGCAAGCATC TCTGACCATCTACCTGGCAAAGACCTGCAGGCCATGAGGACCAGTCAACGACAGTGAGAGGACGTGAGAG GGTAAATCCCTGCACCCAGCAGTATTATTTCCAACCCTGCCGTCCCTGCAAACCAGCCCAAGGGGTAACC GTAAGCGGATGCCTGTATGGCTGCCTTACTGATGCCACGCAGGAACAAAGGCATGAGGACTCGACTGGGG TGCCTGTCACACAAATCAGACTCCTGCAGTGACTTCACTGCCATCCTCCCTGACAAACCCAACCGTGCTC TCAAGAGACTCTCCACGGAAGAAGCAACGAGGTGGGCGGAGTCTTTCGATGTGCTTCTCTCTCATAAGTA TGGGGTGGCAGCCTTCCGTGCCTTCTTGAAGACGGAGTTCAGCGAGGAGAACCTGGAGTTCTGGCTGGCC TGCGAGGAGTTCAAGAAGACCAGGTCAACTGCAAAGCTAGTCACCAAGGCCCACAGGATCTTTGAGGAGT TTGTGGATGTGCAGGCTCCACGGGAGGTGAATATCGATTTCCAGACCCGAGAGGCCACGAGGAAGAACAT GCAAGAGCCATCCCTGACTTGTTTTGATCAAGCTCAGGGAAAAGTCCACAGCCTCATGGAGAAAGACTCC TACCCTAGGTTCCTGAGGTCCAAAATGTACTTAGATCTGCTGTCCCAGAGCCAGAGGAGGCTCAGCTAGA CCTCGGAGGGGGACTCTTGGAAGTCACTGGCTTTCCTTTCCCCTTGCTGCCAAGACCATATTCTGAAGTG AAATGTCATAGATGTCCAAAGGCGCTGGGGTTTGGGGTAGAAGGCTGGGGGCGGTGACAAGGGAATGAAG GGCTTTTCCAAAGTATGACCGAGCTGATGGAGCTGGGACTCTATTCCTTCTACCCAGATTTGTGTTTTGG TTAGAGGCAGCACCGCTGCTATCACCCTTCTCTGGGTGGGCCAGTAACTGGCCCTTTATAATGCCTTCGG TCATCTCTATCGAGAAGGCAGATTCACTGTGCCGGGCTAATTTGTAAATAACGCAAATGCAGCTCCCGTG ACCTACACACCACACCCTCCTCAGCAGGATTCCTGGCCTTCACCTTGTCCTTTCCTCAAGGGAGGATTAG CTAGATGCCTCAGTTTCTCAGTTCTGCTGCACTGTTACAACCCAGTGGCCCAGCCTGAGTAACTGGACCT CACAGTGTAGAAGAGAGGTCTTTTTGGAATTCCATTTCCCTAGCATCATTGACAGGTGACCTCTGACAAA GGATATATAATCCCTGGAGTTGGCTGTGTCTTCCATTTCCACGGGACCAATAGGGAGTCTGAGGTCCCCT TTCAGTCTAAGGAATTCATTGAACTTCCTTACATTTGAAATTCTAGAAAGGGTCTTGGGAGATTTCTCCC AGGACTTCTGAGCAGAGCTGTCCTTTTGAAAGATAAGAGTTTGTGAATCTTCTTCAATTCTATTAAGAAC TTTCCTAGAAGCCGAGTGACCAGGGAATGTAGCATCAGTAGTTTTGTGCAATGAGGCTCCGTATGACCTG TCTGTTGCCTAATGTATTCCATGTCCTCACTTTCCTGTGGCATCACATAGCACTGATCTCTTAGGATGAA AGATGGCTTGGCAAAGGGAGGTACATTCCCATAGCATGACAGCTTCCCTAGTGCCTGTTGCTTTCCCTGT CTCTCCACCTCCTTCTTCCATGAAGGGCATGTAACTATGATGGGAAGACTGAGAACCTAGCCTGAGACTC TCATTGCAGCTTGCTTCCTGGACATACCTTCTTAGAATGGGTCCACTTTTGGCTGTTGAGAAATAGCTCC CTTCTTGGTCTCTAGCCTTTGGGACTGACCTGGGAAGATCACTGTGAATACCAGGCTGCGGAAACTCTCC TGCAATGTTTATGCGGTACCCTGGTGGGGTGCTGGCTCCTGGAAACACACCAGGATACTCTTTCTTGGAG GAGGCACGAACATCCTGGAGTCTCTGAAGTTACCCAGGAGAAAGCTGACCCTGCCATCTCCTACAGGGAC AGAAAGATGAATCTTCAGCACAGAGAGCAGAAGATGGAAGATGAACCTAGAAGCTGCGACCTCTGGGTGA CCTGAGAATGTGGTGAAGGCACTGCTGTGATAATTCACAACCAGTCAACTCGGGCCCATTGAAGAGCCAT AAACTTTCAGCTTGGGTGAATGAAATAGTCTGTGACCAAGCTGCCCTAGAAAGCAGGAGGTGAAAGGCTG GGCTGATACTCCCCTTTGTGGAGTGCTAGCCCTTCTAAGACATCCTAGGGTTTGTATTCTGCTCTTGGAG AATTAGTTCCTTCCTTGGTTGTAGCCAGACAAGGCCAAGAAGGCCCCATGAGTCCGTATTAGTGCCAACT GCCCTTCCAAGTGGCACACTGTCATCTGTGAGTGGGTGTTAGTGTCTGGGTGTGAACCTCAAAGAGAGAG AACATCTACTTCCTAGGCCTCACACTGAAGGGACCTGGGGCAGTCATTTAAAAAGAACTCTGAAGCTTCA AATGGTGATCCTAGTCAGAGCACATAGATTTCCCTACCCTGACATAAAAATATTCTTAGCTAAAGCTGCC AGAATTAATGTAATGATTAAATTCTCTCACAGGGTATTTTAAACATTGTTTACATATGAAATGTGCATCT GCTGCCAAATGCTACTGTCCAATATGCGGTGCATATACACTGGACCTGCAGTGATGGAATCATCCCAGAT GGGTCTTCTCAACACTGGCCCCATCCCAATGCAAAACGGCTCCACGCGTGTGGTGTGGCACCCTCCTTTG GGGCCTAGAGTTCTTGCAAGCTCTTGGTGGGATGAAGGCTGTAGATGATGATGTCATGCACCCTGGTGAC TCCTTTCCAAATTGGGGGGGGGGGTCACGGAGAGTAGGTATGAAGGACCAAGTTTGAGTATTCTGAATTT TGTAGCTAGATAAGTTTGTGTGTGTGTCATAGTCCCATTTATGGTACTCCCATGTGTCCACACATACATC TTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTTTGTGTTTCGTTGTGAGTTGTGAGTCTTGGGCAGTA CACCACAGACATGATCTTCCCATGTGAGTAGCTTTTCACATACCCTATCTCCCCTGCTTCTTCTAGAAAG CACAGCGTTTCTATCCCCGATACCTCCTCTTAAGCACTTTGGTCATGCTAGCCCAGGTTTTGGTCTGTGA TGAGACAGAGAAATGTTTACAACATCTAGAGCAATATCCAAGCATACCTCATCTCCGAGCTTCCACGTCT CCCAGCCCCCTCCCCTCATCTCCTCCTCTACGAGCCTCATCTGCCTCACTGGGTTGTCATCACAGATGCC ACCATTTCCATTTGATGTCTTCCTTTGCTCCAGTCATGCGAGTGTGCTGACGACTGGCTCTGGACTCAGG CCAGCCCAGGCAGTAGGACACCGTGCTGTGACTTTCCATCCCAGAGAGACCTGTTGGTCCCACCGGAGTG TTGACTTGCTTTGGGTCTGGTGTGTGGTTGGCCGTTGCTCTTGTGGACTAACTAGATCTCAGTCACTGAC TACTCGAGCGTTCTGGGTTGAAGGGGGGAGTGATACCCTGAAGTAGTATTTATTATTAAGCATGAGCATG AAGAATAGGGGGTCACCTTGAAAGCCCCTCACAAACGCTAACCCCCAGCTTCCACACCCGGAGGAGGTGC TGATCCTATAGACCTAAGCAAGAGGCCCATAAAGCAACATTGAACAAAAGAAAGAAGCTCCTGGATGTGT AATGGCCTGCAGGCACTGGACAGAGATGGCCCAAGACAGTGGGTCTCAGCCTCGCTGCTCACTAGGCTTA CCAGGGGAGCATTAAGAAACAACATCATCATCATCAACAACAAAAAACTTAAGTGTTCAGTTTCTACCAT AGAGTAGCTAAATCGGAGAGGCTCGGAGGGAGCCAGGTGGCAGTAGTTTTTAATGTCTTGCTAGCGATTC CAATGTGCAGATGTGGACAGGAAACGGCAGCCTAAGCAATGAAGAGGAACGGAACTGAGTAAAACAGGGC CCGGCAGCCCACCTGGATGCCAAAAGCACAATAACCAGGCCGCCCTGCCCACTCTGCAGCTGGCTCTCAC GGTGGTTGCCTCCTGCCTTTCAGTCTGACTGGCTCCTTTGAGGTCATGTTTGGGTTCAGGCTAAATGCGA TAGTTGGTAGTAGGTCCGCCAAGGTTGGGGACATCAAGGCACTTAATGGAGAACTGTTTTGCCCTGCTTC CCCGGCCTCTACCACAGCGCTTCCTCCCCAGCCTGCATCATGGACTCCATCTCCGTTTGTCTTCATATAC TCTTGTGTTTGGCCATTGTGTGTCAGGCTGTGCCTCTGTACCCAAGGTCATGCAGTAGGGTGACTAGAAC ATAGCTAGGGAGTGAAAAGTGTCTTGGTAGTGACAGTCGTGATGCAACAGCTTCCAAATTTCTCTGTGGA GGGTGGCCCTTCCTGGATGAAATCTGGGAGGCTACAGTGTGACTCAGACTCCTGCTGTAAGCCCTCATCA TTTTCTTTGGCCCTGTGCTGGATAGGCAGCAAGGAAGCTGCAAGCTGGCTCTGTTTTCTGGTGCTTTCTC CAGAACTTGCTGCTCTGAGAAACCAAAGCTGTGAACAGGCGAATGCTCTCCCAGGTGTTTGTCATGGATG GGCCCGCACCGCCTGGACAGTAGAGAAGCTTTCTCTGCTGGAAGGAGAAGGCATGAGAACCGGGGAAAGG TGGACAAGGTGGAGGGAGCCTGAGGAGGAAGGGGCAAGGCAGGAGAGACTCCCCAGTTGCTTCTCCATTT CCCAGAGGGAAAGGGGGAGGGGGCACATTCATAGGCAGGATGGCCTTCTAGCAAGAACCCCAGAAGTCCG TAGAGCCTGCAGAGGAACTGTGGTTTTCTACCCTTGCCTTCAGTCTGTCAAGTGTCAGCTTTCCTGAGGT CCATCCCCTTCCAGTTAAAACAGGAGAGGTGGTACCAATACTCCTGGCGCTGGGCGTCTGTGCCACTGTG TCACTTGGCATGAGACAAGGAGGGAGAAGCGAAGAGGAGAGATGGCTTTCTGTCCCTGTGGCTTCTCAAA GACTCTACAGGATGCCGTAGGGGCACAATGGGATACGTCAGGATGGGACTCCGGGCCTCGCCAGGTTTTG GGTTTGGGGTCCTCTCAATAAACTGTTTATTTCTTGAACTTAACCCCTCTGCTCCTTCCCCTCTGCCAGG TTACAAGGCGAGTAGGCCCTACATAGGCCCCAACCACAGTAGCCTTAGCTGGTCACTCACGGAGCACAAC GCAGCTCATCTGCCCTATAAACCGCTTGGCCGACGAATCCTCATTGAGTTCTTTCATTACCATGTAAAGT GAAATACACTCACTCACCTTTACTATACACAGGCTGTGAGAACATAATAAACAAAACCTGAACAAGCAAA AAAAAAAAAAAAAAAAAAAA
• Restriction Sites: AscI-NotI
• ACCN: NM_026380
• Insert Size: 543 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: BC065056, AAH65056
• RefSeq Size: 5760 bp
• RefSeq ORF: 543 bp
• Locus ID: 67792
• UniProt ID: Q8BXT1
• Cytogenetics: 1 65.41 cM
• Gene Summary: Regulates G protein-coupled receptor signaling cascades, including signaling via muscarinic acetylcholine receptor CHRM2 and dopamine receptor DRD2. Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits, thereby driving them into their inactive GDP-bound form. Modulates the activity of potassium channels that are activated in response to DRD2 and CHRM2 signaling.[UniProtKB/Swiss-Prot Function]