Coq8a (NM_023341) Mouse Untagged Clone

CAT#: MC201482

Adck3 (untagged) - Mouse aarF domain containing kinase 3 (Adck3), nuclear gene encoding mitochondrial protein, transcript variant 1, (10ug)

Specifications

Product Data

• Type: Mouse Untagged Clone
• Tag: Tag Free
• Symbol: Coq8a
• Synonyms: 4632432J16Rik; Adck3; AI462003; Cabc1; mKIAA0451
• Vector: PCMV6-Kan/Neo
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >BC030937 sequence for NM_023341
  GGTAAACAGAAGCGGAGAGTGTGCGGAGCGCTCGCAGCGGGGCGAGCGCGCGGAGGCGTTGCGTTGCGGA CGGAGGAGCTACCTTCCTGCAGCCCGCTCTGAAGGATGGCTGCTATGTTGGGGGATGCCATCATGGTGGC CAAAGGCCTTGCCAAGCTGACCCAAGCAGCGGTGGAAACCCACTTGCAGAACCTGGGCCTTGGTGGGGAG CTCCTCCTGGCGGCCAGGGCCCTGCAGTCTACAGCTGTGGAGCAGTTCAGCATGGTCTTCGGGAAGGTGC AGGGTCAGGATAAGCATGAAGATTCATATGCCACTGAGAACTTTGAAGATCTGGAAGCCGAAGTTCAGTT CTCAACACCACAGGCAGCTGGAACCTCCCTGGACTTCTCTGCGGCCTCTTCCCTGGACCAGTCACTGTCT CCATCCCACAGTCAGGGACCGGCCCCTGCCTATGCTTCCAGTGGGCCTTTCAGGGAAGCTGGGCTCCCTG GACAGGCCACCTCTCCTATGGGCAGAGTCAATGGAAGGCTCTTTGTAGATCACAGAGACTTGTTCTTGGC CAACGGCATCCAGCGAAGATCCTTCCACCAGGACCAGTCCTCCGTGGGAGGCCTCACGGCTGAAGACATT GAAAAGGCCCGGCAGGCCAAGGCTCGCCCTGAGAGCAAGCCACACAAGCAGATGCTCAGTGAGCGGGCTC GGGAGCGGAAGGTGCCAGTTACCCGGATTGGGCGGTTGGCCAACTTTGGAGGTCTGGCTGTAGGTCTGGG AATTGGGGCGTTGGCTGAAGTTGCCAAGAAGAGTCTGCGTTCTGAGAACTCCACAGGAAAAAAAGCCGTG CTGGATTCTAGCCCCTTCCTGTCAGAGGCAAATGCAGAGCGCATTGTGAGTACACTGTGCAAGGTGCGTG GGGCCGCACTGAAGCTGGGCCAGATGCTGAGCATCCAGGATGATGCCTTCATCAACCCTCACCTGGCCAA GATCTTTGAGCGGGTGAGGCAGAGTGCTGACTTCATGCCACTGAAACAGATGACGAAAACCCTCAACAGC GACCTGGGCCCCCACTGGAGGGACAAGCTGGAGTACTTTGAAGAGCGGCCCTTTGCAGCGGCCTCCATAG GGCAGGTGCACCTGGCCCGCATGAAGGGTGGCCGTGAGGTGGCCATGAAGATCCAGTACCCTGGTGTGGC CCAGAGCATTAACAGTGACGTCAACAACCTCATGGCTGTGCTGAACATGAGTAACATGCTTCCAGAAGGC CTGTTCCCTGAGCACCTGATTGATGTGCTGAGACGGGAGCTTACCCTTGAGTGTGACTACCAGCGGGAGG CTGCCTATGCCAAGAAGTTCAGGGAACTGCTGAAGGACCATCCCTTCTTCTATGTGCCTGAGATTGTGGA TGAGTTGTGCAGTCCCCATGTGCTGACCACAGAGCTCATATCAGGCTTCCCCTTGGACCAGGCAGAAGGG CTGAGCCAGGAAGTGAGGAATGAGATCTGCTACAACATTTTGGTGCTGTGCCTGAGAGAGCTGTTTGAGT TCCATGTCATGCAGACTGACCCCAACTGGTCCAATTTCTTTTATGACCCTCAGCAGCACAAGGTGGCTCT CCTGGACTTCGGCGCAACTAGAGAATATGACAGATCCTTTACTGACCTCTACATTCAGGTCATCCGGGCC GCTGCTGACCAGGACAGGGAGGCAGTGCTAAAGAAATCCATAGAGATGAAGTTCCTTACCGGTTATGAGG TCAAGGCCATGGAGGATGCTCACCTGGATGCTATTCTCATCCTGGGGGAGGCCTTTGCCTCCGAAGAGCC CTTCGACTTCGGTACCCAGAGCACTACTGAGAAGATCCACAACCTGATTCCCGTCATGCTGAAGCACCGC CTCATCCCACCCCCAGAGGAGACCTACTCTCTGCACCGCAAGATGGGTGGCTCTTTCCTCATCTGCTCTA AGCTGAAGGCCCGCTTCCCCTGTAAGGCCATGTTCGAGGAAGCGTACAGTAACTACTGCAGGATGAAGTC TGGGCTGCAGTAGGTGAGGTGTGGTCCAGGCTAACTAGGGGCCATGCCCTCCTTCAGGCTCAGTCAAGCA GAGGGAGGACGTTGAAAGGGAGCCACGGCCTCTATGAATAGGAAGAGAGCGTTGCGTAGACCCTCCTATT GCTTCTGTACTGTCCAGACAAAAAGGCAGGCTTCTTTTGCCATCTCCTCCCTGCTGTGGATGTACAACCA GGAACAGGAGCAATGCAGTACTAAACTCAACACAGCCACCTTTGGGGTCTAGTTGGCCATGGGAATGAAT TGTGTGTTTCTGGGTGAGCTTATGTCCCTGCCCTTTGCCACCCCAGCCTGTGGCCTGGAGCTAGAAGCTC AGGACAGCAGGGTAGCCACCCTAGCTCAGTCTCAGCATGGACAACAGACCCTTTTAAAAGCAGGGCTGAC ATTGGATGAGCAGCAGGGCTCCAGCATGCCCCAGGAGAGGGAGCTATCACCCCACCCCAGGGGAGCGACA CAGGCTCTTTGTTTGTATGTCTTGTAATTACACATTCATACCTTTGCGTTCAATAAAGAAGTGCGTTGGG GACTGCCAAAAAAAAAAAAAAA
• Restriction Sites: RsrII-NotI
• ACCN: NM_023341
• Insert Size: 1938 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: BC030937, AAH30937
• RefSeq Size: 2612 bp
• RefSeq ORF: 1938 bp
• Locus ID: 67426
• UniProt ID: Q60936
• Cytogenetics: 1 H4
• Gene Summary: Atypical kinase involved in the biosynthesis of coenzyme Q, also named ubiquinone, an essential lipid-soluble electron transporter for aerobic cellular respiration (PubMed:27499294). Its substrate specificity is unclear: does not show any protein kinase activity (PubMed:27499294). Probably acts as a small molecule kinase, possibly a lipid kinase that phosphorylates a prenyl lipid in the ubiquinone biosynthesis pathway, as suggested by its ability to bind coenzyme Q lipid intermediates (By similarity). Shows an unusual selectivity for binding ADP over ATP (By similarity).[UniProtKB/Swiss-Prot Function]
  Transcript Variant: This variant (1) represents the longest transcript. Both variants 1 and 2 encode the same isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data because no single transcript from the same strain was available for the full length of the gene. The extent of this transcript is supported by transcript alignments.