AMACR Mouse Monoclonal Antibody [Clone ID: OTI3E10]

CAT#: TA808476

AMACR mouse monoclonal antibody, clone OTI3E10 (formerly 3E10)


 Product Datasheet for 'TA808476'

  View other "OTI3E10" antibodies (2)

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USD 360.00


Availability*
In Stock

Size
    • 100 ul


Specifications

Product Data
Clone Name OTI3E10
Applications IHC, WB
Recommend Dilution IHC 1:150
Reactivity Human
Host Mouse
Clonality Monoclonal
Immunogen Full length human recombinant protein of human AMACR (NP_055139) produced in HEK293T cell.
Isotype IgG1
Formulation PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration 1 mg/ml
Purification Purified from cell culture supernatant by affinity chromatography
Predicted Protein Size 42.2 kDa
Gene Name alpha-methylacyl-CoA racemase
Background This gene encodes a racemase. The encoded enzyme interconverts pristanoyl-CoA and C27-bile acylCoAs between their (R)- and (S)-stereoisomers. The conversion to the (S)-stereoisomers is necessary for degradation of these substrates by peroxisomal beta-oxidation. Encoded proteins from this locus localize to both mitochondria and peroxisomes. Mutations in this gene may be associated with adult-onset sensorimotor neuropathy, pigmentary retinopathy, and adrenomyeloneuropathy due to defects in bile acid synthesis. Alternatively spliced transcript variants have been described. Read-through transcription also exists between this gene and the upstream neighboring C1QTNF3 (C1q and tumor necrosis factor related protein 3) gene. [provided by RefSeq, Mar 2011]
Synonyms AMACRD; CBAS4; RACE; RM
Reference Data
Protein Families Druggable Genome
Protein Pathways Metabolic pathways, Primary bile acid biosynthesis

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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