Apc2 (ANAPC2) Mouse Monoclonal Antibody [Clone ID: OTI1A6]

CAT#: TA503411

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ANAPC2 (Apc2) mouse monoclonal antibody, clone OTI1A6 (formerly 1A6)

Size: 30 ul 100 ul

Formulation: Standard Carrier-Free

Conjugation: Unconjugated Biotin HRP



USD 447.00

In Stock*

Size
    • 100 ul

Frequently bought together (3)
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Specifications

Product Data
Clone Name OTI1A6
Applications FC, IF, IHC, WB
Recommended Dilution WB 1:500~2000, IHC 1:150, IF 1:100, FLOW 1:100
Reactivities Human, Monkey, Mouse, Rat
Host Mouse
Isotype IgG2a
Clonality Monoclonal
Immunogen Full length human recombinant protein of human ANAPC2(NP_037498) produced in HEk293 cell.
Formulation PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration 0.74 mg/ml
Purification Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Predicted Protein Size 93.6 kDa
Gene Name anaphase promoting complex subunit 2
Background A large protein complex, termed the anaphase-promoting complex (APC), or the cyclosome, promotes metaphase-anaphase transition by ubiquitinating its specific substrates such as mitotic cyclins and anaphase inhibitor, which are subsequently degraded by the 26S proteasome. Biochemical studies have shown that the vertebrate APC contains eight subunits. The composition of the APC is highly conserved in organisms from yeast to humans. The product of this gene is a component of the complex and shares sequence similarity with a recently identified family of proteins called cullins, which may also be involved in ubiquitin-mediated degradation. [provided by RefSeq]
Synonyms APC2
Reference Data
Protein Families Druggable Genome
Protein Pathways Cell cycle, Oocyte meiosis, Progesterone-mediated oocyte maturation, Ubiquitin mediated proteolysis
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