LAT2(SLC7A8) Mouse Monoclonal Antibody [Clone ID: OTI5A9]

CAT#: TA500503

anti-SLC7A8 (LAT2) mouse monoclonal antibody, clone OTI5A9 (formerly 5A9)

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 Product Datasheet for 'TA500503'

USD 350


Availability*
In Stock

Size
    • 100 ul

Specifications

Product Data
Clone Name OTI5A9
Applications WB, IHC, IF, IP, FC
Recommend Dilution WB 1:500, IHC 1:50, IF 1:100, FLOW 1:100, IP 2ug/500ul
Reactivity Human
Host Mouse
Clonality Monoclonal
Immunogen Full-length protein expressed in 293T cell transfected with human SLC7A8 expression vector .
Isotype IgG1
Formulation PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration 1.00mg/ml
Purification Purified from cell culture supernatant by affinity chromatography
Predicted Protein Size 58.4 kDa
Gene Name solute carrier family 7 member 8
Background Sodium-independent, high-affinity transport of small and large neutral amino acids such as alanine, serine, threonine, cysteine, phenylalanine, tyrosine, leucine, arginine and tryptophan, when associated with SLC3A2/4F2hc. Acts as an amino acid exchanger. Has higher affinity for L-phenylalanine than LAT1 but lower affinity for glutamine and serine. L-alanine is transported at physiological concentrations. Plays a role in basolateral (re)absorption of neutral amino acids. Involved in the uptake of methylmercury (MeHg) when administered as the L-cysteine orD,L-homocysteine complexes, and hence plays a role in metal ion homeostasis and toxicity. Involved in the cellular activity of small molecular weight nitrosothiols, via the stereoselective transport of L-nitrosocysteine (L-CNSO) across the transmembrane. Plays an essential role in the reabsorption of neutral amino acids from the epithelial cells to the bloodstream in the kidney.
Synonyms LAT2|LPI-PC1
Reference Data
Protein Families Transmembrane, Druggable Genome
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

Citations