LAT2 (SLC7A8) Mouse Monoclonal Antibody [Clone ID: OTI5A9]

CAT#: CF500503

Carrier-free (BSA/glycerol-free) SLC7A8 mouse monoclonal antibody, clone OTI5A9 (formerly 5A9)

Formulation: Standard Carrier-Free


  View other "OTI5A9" antibodies (4)

USD 600.00

3 Days*

Size
    • 100 ug

Frequently bought together (1)
Biotinylation Labelling Kit formatted 4 x 0.05mg
    • 200 ug

USD 412.00

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Specifications

Product Data
Clone Name OTI5A9
Applications FC, IF, IHC, IP, WB
Recommended Dilution WB 1:500, IHC 1:50, IF 1:100, FLOW 1:100, IP 2ug/500ul
Reactivities Human, Mouse, Rat
Host Mouse
Isotype IgG1
Clonality Monoclonal
Immunogen Full-length protein expressed in 293T cell transfected with human SLC7A8 expression vector .
Formulation Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Reconstitution Method For reconstitution, we recommend adding 100uL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiment, we strongly recommend performing another round of desalting process. (OriGene recommends Zeba Spin Desalting Columns, 7KMWCO from Thermo Scientific)
Purification Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Predicted Protein Size 58.4 kDa
Gene Name Homo sapiens solute carrier family 7 member 8 (SLC7A8), transcript variant 1, mRNA.
Background Sodium-independent, high-affinity transport of small and large neutral amino acids such as alanine, serine, threonine, cysteine, phenylalanine, tyrosine, leucine, arginine and tryptophan, when associated with SLC3A2/4F2hc. Acts as an amino acid exchanger. Has higher affinity for L-phenylalanine than LAT1 but lower affinity for glutamine and serine. L-alanine is transported at physiological concentrations. Plays a role in basolateral (re)absorption of neutral amino acids. Involved in the uptake of methylmercury (MeHg) when administered as the L-cysteine orD,L-homocysteine complexes, and hence plays a role in metal ion homeostasis and toxicity. Involved in the cellular activity of small molecular weight nitrosothiols, via the stereoselective transport of L-nitrosocysteine (L-CNSO) across the transmembrane. Plays an essential role in the reabsorption of neutral amino acids from the epithelial cells to the bloodstream in the kidney.
Synonyms LAT2; LPI-PC1
Reference Data
Protein Families Druggable Genome, Transmembrane

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.