PDGF Receptor alpha (PDGFRA) Rabbit Polyclonal Antibody

CAT#: TA347459

Rabbit Polyclonal Anti-PDGFRalpha Antibody

Product Images

Western blot analysis on 293 cell lysate using PDGFRalpha Antibody

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB: 1:500-1:3000
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: The immunogen for anti-PDGFRalpha Antibody: A synthesized peptide derived from human PDGFRalpha
• Formulation: Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20?. Stable for 12 months from date of receipt
• Concentration: lot specific
• Purification: Affinity-chromatography
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 140 kDa
• Gene Name: platelet derived growth factor receptor alpha
• Database Link:
  NP_006197
  Entrez Gene 18595 MouseEntrez Gene 25267 RatEntrez Gene 5156 Human
  UniProt ID P16234
• Background: PDGFRa a receptor tyrosine kinase of the PDGFR family that binds members of the platelet-derived growth factor family. The identity of the growth factor bound determines whether the functional receptor is a homodimer or a heterodimer, composed of both PDGFR-alpha and -beta. Ligand binding induces receptor dimerization and autophosphorylation.
• Synonyms: CD140A; PDGFR-2; PDGFR2; RHEPDGFRA
• Note: PDGFRalpha antibody detects endogenous levels of total PDGFRalpha

Reference Data

• Protein Families: Druggable Genome, ES Cell Differentiation/IPS, Protein Kinase, Transmembrane
• Protein Pathways: Calcium signaling pathway, Colorectal cancer, Cytokine-cytokine receptor interaction, Endocytosis, Focal adhesion, Gap junction, Glioma, MAPK signaling pathway, Melanoma, Pathways in cancer, Prostate cancer, Regulation of actin cytoskeleton