Cytochrome C (CYCS) Rabbit Polyclonal Antibody
Frequently bought together (3)
Transient overexpression lysate of cytochrome c, somatic (CYCS), nuclear gene encoding mitochondrial protein
USD 436.00
Recombinant protein of human cytochrome c, somatic (CYCS), nuclear gene encoding mitochondrial protein, 20 µg
USD 867.00
Other products for "Cytochrome C"
Specifications
Product Data | |
Applications | IF, IHC, WB |
Recommended Dilution | WB 1:500 - 1:1000;IHC 1:50 - 1:200 |
Reactivities | Human, Mouse, Rat |
Host | Rabbit |
Isotype | IgG |
Clonality | Polyclonal |
Immunogen | Recombinant protein of human CYCS |
Formulation | Store at -20C or -80C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3 |
Concentration | lot specific |
Purification | Affinity purification |
Conjugation | Unconjugated |
Storage | Store at -20°C as received. |
Stability | Stable for 12 months from date of receipt. |
Predicted Protein Size | 12 kDa |
Gene Name | cytochrome c, somatic |
Database Link | |
Background | Cytochrome c is a well conserved electron-transport protein and is part of the respiratory chain localized to mitochondrial intermembrane space. Upon apoptotic stimulation, cytochrome c released from mitochondria associates with procaspase-9 (47 kDa)/Apaf 1. This complex processes caspase-9 from inactive proenzyme to its active form. This event further triggers caspase-3 activation and eventually leads to apoptosis. |
Synonyms | CYC; HCS; THC4 |
Reference Data | |
Protein Families | Druggable Genome |
Protein Pathways | Alzheimer's disease, Amyotrophic lateral sclerosis (ALS), Apoptosis, Colorectal cancer, Huntington's disease, p53 signaling pathway, Parkinson's disease, Pathways in cancer, Small cell lung cancer, Viral myocarditis |
Documents
Product Manuals |
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complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.