TAT Rabbit Polyclonal Antibody
Specifications
Product Data | |
Applications | IHC, WB |
Recommended Dilution | WB: 200-1000 WB positive control: Human normal liver tissue IHC: 25-100 Positive control: Human colon cancer Predicted cell location: Cytoplasm |
Reactivities | Human, Mouse, Rat |
Host | Rabbit |
Isotype | IgG |
Clonality | Polyclonal |
Immunogen | Fusion protein corresponding to a region derived from C terminal 250 amino acids of human tyrosine aminotransferase |
Formulation | PBS pH7.3, 0.05% NaN3, 50% glycerol |
Concentration | lot specific |
Purification | Antigen affinity purification |
Conjugation | Unconjugated |
Storage | Store at -20°C as received. |
Stability | Stable for 12 months from date of receipt. |
Gene Name | tyrosine aminotransferase |
Database Link | |
Background | This nuclear gene encodes a mitochondrial protein tyrosine aminotransferase which is present in the liver and catalyzes the conversion of L-tyrosine into p-hydroxyphenylpyruvate. Mutations in this gene cause tyrosinemia (type II; Richner-Hanhart syndrome); a disorder accompanied by major skin and corneal lesions; with possible mental retardation. A regulator gene for tyrosine aminotransferase is X-linked. |
Synonyms | cytosolic; tyrosine aminotransferase |
Reference Data | |
Protein Families | Druggable Genome, Embryonic stem cells, ES Cell Differentiation/IPS |
Protein Pathways | Cysteine and methionine metabolism, Metabolic pathways, Phenylalanine, tyrosine and tryptophan biosynthesis, Phenylalanine metabolism, Tyrosine metabolism, Ubiquinone and other terpenoid-quinone biosynthesis |
Documents
Product Manuals |
FAQs |
SDS |
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