LAIR1 Mouse Monoclonal Antibody [Clone ID: NKTA255]

CAT#: SM2048F

LAIR1 mouse monoclonal antibody, clone NKTA255, FITC

Product Images

Staining of Human peripheral blood lymphocytes with Mouse Anti Human CD305 antibody FITC conjugated.

Specifications

Product Data

• Clone Name: NKTA255
• Applications: FC
• Recommended Dilution: Flow Cytometry: Use 10 µl of neat antibody to label 10e6 cells in 100 µl.
• Reactivities: Human
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: NK cells lines B12.100 and AM.25.
• Specificity: This antibody recognizes leukocyte-associated Ig-like receptor-1 (LAIR-1).
  Clone NKTA255 is reported to inhibit NK cell triggering via CD16 molecules (Ref.3)
• Formulation: PBS, pH 7.4 containing 0.09% Sodium Azide and 1% BSA
  Label: FITC
  State: Liquid purified IgG fraction
  Label: Fluorescein Isothiocyanate Isomer 1
• Concentration: lot specific
• Purification: Affinity Chromatography on Protein G
• Conjugation: FITC
• Storage: Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  This product is photosensitive and should be protected from light.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: leukocyte associated immunoglobulin like receptor 1
• Database Link:
  Entrez Gene 3903 Human
  UniProt ID Q6GTX8
• Background: LAIR-1 is a 40kD cell surface molecule that functions as an inhibitory receptor on natural killer cells, monocytes and T cells. LAIR-1, otherwise known as CD305, is also expressed by other haematopoeitic cells including B cells, but is not expressed by nonhaematopoietic, platelets or erythrocytes.
• Synonyms: LAIR-1, hLAIR1