Leukemias are a group of hematologic disorders characterized by the dysfunctional proliferation and development of leukocytes. Acute Lymphoblastic Leukemia (ALL), Acute Myelogenous Leukemia (AML), Chronic Lymphocytic Leukemia (CLL) and Chronic Myelogenous Leukemia (CML) are the 4 major subtypes of leukemia.
CD Markers in Leukemia
The CD (cluster of differentiation) markers are frequently used in differential diagnosis of leukemia. Detection of changes in CD marker expression in leukemia is critical for understand the primary mechanisms initiating these changes.
OriGene offers a range of tools to analyze CD markers including cDNA clones, antibodies, overexpression cell lysates and more. Click the buttons below for details.CD7 CD10 CD13 CD20 CD23 CD33 CD52 CD79a CD138 CD205
Leukemia markers stained with OriGene’s Ultra Specific Antibodies
Leukemia Stems cells in Acute Myeloid Leukemia (AML)
Leukemia stem cells (LSCs)play a critical role in the initiation, progression and treatment resistance in AML. Developing markers for LSCs and understanding the molecular mechanisms of LSCs is critical for developing better targeting strategies.
OriGene offers a range of tools to analyze CD markers including cDNA clones, antibodies, overexpression cell lysates and more. Click the buttons below for details.CD34 CD38 CD123 TIM3 CD9 HDACs NF-kB HIF-1α β-catenin
Leukemia Stem Cell markers stained with OriGene’s Ultra Specific and TrueMAB Antibodies
Explore the gene specific tools for leukemia research
- Leukemia, Iyengar and Shimanovsky, https://pubmed.ncbi.nlm.nih.gov/32809325/
- The biomarkers of LSCs in AML, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5388677/pdf/sci-04-2017.02.10.pdf