CDK1 (NM_001786) Human Recombinant Protein

CAT#: TP762400

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Purified recombinant protein of Human cyclin-dependent kinase 1 (CDK1), transcript variant 1, full length, with N-terminal His tag, expressed in E.coli, 50ug



  View other "CDK1" proteins (4)

USD 205.00


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    • 50 ug


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Product Data
Description Purified recombinant protein of Human cyclin-dependent kinase 1 (CDK1), transcript variant 1, full length, with N-terminal His tag, expressed in E.coli, 50ug
Species Human
Expression Host E. coli
Expression cDNA Clone or AA Sequence A DNA sequence encoding the full length of CDK1
Tag N-His
Predicted MW 34.1 kDa
Concentration >50 ug/mL as determined by microplate BCA method
Purity >80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 50mM Tris, pH8.0, 8M Urea
Storage Store at -80°C after receiving vials.
Stability Stable for at least 1 year from receipt of products under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Reference Data
RefSeq NP_001777
Locus ID 983
UniProt ID P06493, I6L9I5
Cytogenetics 10q21.2
Refseq Size 1923
Refseq ORF 891
Synonyms CDC2; CDC28A; P34CDC2
Summary The protein encoded by this gene is a member of the Ser/Thr protein kinase family. This protein is a catalytic subunit of the highly conserved protein kinase complex known as M-phase promoting factor (MPF), which is essential for G1/S and G2/M phase transitions of eukaryotic cell cycle. Mitotic cyclins stably associate with this protein and function as regulatory subunits. The kinase activity of this protein is controlled by cyclin accumulation and destruction through the cell cycle. The phosphorylation and dephosphorylation of this protein also play important regulatory roles in cell cycle control. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009]
Protein Families Druggable Genome, Protein Kinase, Stem cell - Pluripotency
Protein Pathways Cell cycle, Gap junction, Oocyte meiosis, p53 signaling pathway, Progesterone-mediated oocyte maturation

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