SDF1 (CXCL12) (NM_199168) Human Recombinant Protein

CAT#: TP723784

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Purified recombinant protein of Human chemokine (C-X-C motif) ligand 12 (CXCL12 / SDF-1alpha), transcript variant 1


 Product Datasheet for 'TP723784'

  View other "CXCL12" proteins (13)

USD 245.00


Availability*
5 Days

Size
    • 10 ug


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Specifications

Product Data
Description Purified recombinant protein of Human chemokine (C-X-C motif) ligand 12 (CXCL12 / SDF-1alpha), transcript variant 1
Species Human
Expression Host E. coli
Expression cDNA Clone or AA Sequence Human SDF, the region of Lys22-Lys89, from gene Accession# NM_199168
Tag Tag Free
Predicted MW 8.0 kDa
Concentration Protein formulated and vialed at >50 ug/mL in specified buffer
Purity >98%, as determined by Coomassie stained SDS-PAGE.
Buffer 20mM Tris pH8.0, 0.5M NaCl
Bioactivity The ED50 is 80 - 120 ng/ml, corresponding to a specific activity of 1.25-0.83 x 10^4 units/mg.
Endotoxin Less than 0.1 EU/µg (<0.01 ng/µg) protein as determined by the LAL method.
Reference Data
RefSeq NP_954637
Locus ID 6387
Refseq Size 1937
Cytogenetics 10q11.21
Refseq ORF 267
Synonyms IRH; PBSF; SCYB12; SDF1; TLSF; TPAR1
Summary This antimicrobial gene encodes a stromal cell-derived alpha chemokine member of the intercrine family. The encoded protein functions as the ligand for the G-protein coupled receptor, chemokine (C-X-C motif) receptor 4, and plays a role in many diverse cellular functions, including embryogenesis, immune surveillance, inflammation response, tissue homeostasis, and tumor growth and metastasis. Mutations in this gene are associated with resistance to human immunodeficiency virus type 1 infections. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2014]
Protein Families Druggable Genome, ES Cell Differentiation/IPS, Secreted Protein
Protein Pathways Axon guidance, Chemokine signaling pathway, Cytokine-cytokine receptor interaction, Leukocyte transendothelial migration

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BOGO Free lysates
68 Mouse Clones
HUMAN PROREINS 101