SDF1 (CXCL12) Rabbit Polyclonal Antibody

CAT#: TA326687

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Rabbit Polyclonal CXCL12 Antibody



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USD 440.00


Availability*
5 Days

Size
    • 100 ug


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Specifications

Product Data
Applications IHC, WB
Recommended Dilution WB: 1 - 2 ug/mL, ICC: 5 ug/mL
Reactivity Human, Mouse
Host Rabbit
Isotype IgG
Clonality Polyclonal
Immunogen CXCL12 antibody was raised against a 16 amino acid peptide near the center of human CXCL12
Formulation CXCL12 antibody is supplied in PBS containing 0.02% sodium azide.
Concentration 1 mg/ml
Purification CXCL12 antibody is affinity chromatography purified via peptide column.
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Predicted Protein Size Predicted: 15 kDa; Observed: 18 kDa
Gene Name C-X-C motif chemokine ligand 12
Background The CXCL12 protein, also known as SDF1, is a stromal cell-derived alpha chemokine member of the intercrine family. CXCL12 functions as the ligand for the G-protein coupled receptor, chemokine (C-X-C motif) receptor 4 (CXCR4) and CXCR7, and plays a role in many diverse cellular functions, including embryogenesis, immune surveillance, inflammation response, tissue homeostasis, and tumor growth and metastasis (reviewed in 1). Mutations in this gene are associated with resistance to human immunodeficiency virus type 1 infections (2).
Synonyms IRH; PBSF; SCYB12; SDF1; TLSF; TPAR1
Reference Data
Protein Families Druggable Genome, ES Cell Differentiation/IPS, Secreted Protein
Protein Pathways Axon guidance, Chemokine signaling pathway, Cytokine-cytokine receptor interaction, Leukocyte transendothelial migration
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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