SDF1 (CXCL12) (NM_199168) Human Mass Spec Standard

CAT#: PH307891

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CXCL12 MS Standard C13 and N15-labeled recombinant protein (NP_954637)



  View other "CXCL12" proteins (10)

USD 2,260.00


Availability*
3 Weeks

Size
    • 10 ug


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Specifications

Product Data
Description CXCL12 MS Standard C13 and N15-labeled recombinant protein (NP_954637)
Tag C-Myc/DDK
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC207891
Predicted MW 9.9 kDa
Protein Sequence
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration 50 ug/ml as determined by BCA
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 100 mM glycine, 25 mM Tris-HCl, pH 7.3. Store at -80°C. Avoid repeated freeze-thaw cycles. Stable for 3 months from receipt of products under proper storage and handling conditions.
Reference Data
RefSeq NP_954637
RefSeq Size 1937
RefSeq ORF 267
Synonyms IRH; PBSF; SCYB12; SDF1; TLSF; TPAR1
Locus ID 6387
UniProt ID P48061
Cytogenetics 10q11.21
Summary This antimicrobial gene encodes a stromal cell-derived alpha chemokine member of the intercrine family. The encoded protein functions as the ligand for the G-protein coupled receptor, chemokine (C-X-C motif) receptor 4, and plays a role in many diverse cellular functions, including embryogenesis, immune surveillance, inflammation response, tissue homeostasis, and tumor growth and metastasis. Mutations in this gene are associated with resistance to human immunodeficiency virus type 1 infections. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2014]
Protein Families Druggable Genome, ES Cell Differentiation/IPS, Secreted Protein
Protein Pathways Axon guidance, Chemokine signaling pathway, Cytokine-cytokine receptor interaction, Leukocyte transendothelial migration

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