SDF1 (CXCL12) (NM_000609) Human Recombinant Protein

CAT#: TP750013

Recombinant protein of human stromal cell-derived factor-1 (SDF-1) produced in E. coli.

Product images

Specifications

Product Data

• Description: Recombinant protein of human stromal cell-derived factor-1 (SDF-1) produced in E. coli.
• Species: Human
• Expression Host: E. coli
• Expression cDNA Clone or AA Sequence: A DNA sequence encoding the region (Lys22-Lys89) of human SDF-1
• Tag: Tag Free
• Predicted MW: 8 kDa
• Concentration: Resuspend the protein to the desired concentration in proper buffer.
• Purity: >95% as determined by SDS-PAGE and Coomassie blue staining
• Buffer: Lyophilized from a sterile solution containing 20 mM phosphate buffer, pH7.4.
• Endotoxin: < 0.1 EU per 1 µg of the protein by the LAL
• Storage: Store at -80°C.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.

Reference Data

• RefSeq: NP_000600
• Locus ID: 6387
• UniProt ID: P48061
• Cytogenetics: 10q11.21
• Refseq Size: 3560
• Refseq ORF: 279
• Synonyms: IRH; PBSF; SCYB12; SDF1; TLSF; TPAR1
• Summary: This antimicrobial gene encodes a stromal cell-derived alpha chemokine member of the intercrine family. The encoded protein functions as the ligand for the G-protein coupled receptor, chemokine (C-X-C motif) receptor 4, and plays a role in many diverse cellular functions, including embryogenesis, immune surveillance, inflammation response, tissue homeostasis, and tumor growth and metastasis. Mutations in this gene are associated with resistance to human immunodeficiency virus type 1 infections. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2014]
• Protein Families: Druggable Genome, ES Cell Differentiation/IPS, Secreted Protein
• Protein Pathways: Axon guidance, Chemokine signaling pathway, Cytokine-cytokine receptor interaction, Leukocyte transendothelial migration