Syndecan 1 (SDC1) (NM_002997) Human Recombinant Protein
Purified recombinant protein of Human syndecan 1 (SDC1), transcript variant 2
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Specifications
Product Data | |
Description | Purified recombinant protein of Human syndecan 1 (SDC1), transcript variant 2 |
Species | Human |
Expression Host | HEK293 |
Expression cDNA Clone or AA Sequence | QIVATNLPPEDQDGSGDDSDNFSGSGAGALQDITLSQQTPSTWKDTQLLTAIPTSPEPTGLEATAASTSTLPAGEGPKEGEAVVLPEVEPGLTAREQEATPRPRETTQLPTTHQASTTTATTAQEPATSHPHRDMQPGHHETSTPAGPSQADLHTPHTEDGGPSATERAAEDGASSQLPAAEGSGEQDFTFETSGENTAVVAVEPDRRNQSPVDQGATGASQGLLDRKEVDHHHHHH |
Tag | C-His |
Predicted MW | 20.39 kDa |
Concentration | lot specific |
Purity | >95% as determined by SDS-PAGE and Coomassie blue staining |
Buffer | Lyophilized from a 0.2 µM filtered solution of 20mM PB,150mM NaCl,pH7.4 |
Endotoxin | Endotoxin level is < 0.1 ng/µg of protein (< 1 EU/µg) |
Storage | Store at -80°C. |
Stability | Stable for at least 6 months from date of receipt under proper storage and handling conditions. |
Reference Data | |
RefSeq | NP_002988 |
Locus ID | 6382 |
Refseq Size | 3217 |
Cytogenetics | 2p24.1 |
Refseq ORF | 930 |
Synonyms | CD138; SDC; SYND1; syndecan |
Summary | The protein encoded by this gene is a transmembrane (type I) heparan sulfate proteoglycan and is a member of the syndecan proteoglycan family. The syndecans mediate cell binding, cell signaling, and cytoskeletal organization and syndecan receptors are required for internalization of the HIV-1 tat protein. The syndecan-1 protein functions as an integral membrane protein and participates in cell proliferation, cell migration and cell-matrix interactions via its receptor for extracellular matrix proteins. Altered syndecan-1 expression has been detected in several different tumor types. While several transcript variants may exist for this gene, the full-length natures of only two have been described to date. These two represent the major variants of this gene and encode the same protein. [provided by RefSeq, Jul 2008] |
Protein Families | Druggable Genome, ES Cell Differentiation/IPS, Transmembrane |
Protein Pathways | Cell adhesion molecules (CAMs), ECM-receptor interaction |
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Other Versions
SKU | Description | Size | Price |
---|---|---|---|
LC423561 | SDC1 HEK293T cell transient overexpression lysate (as WB positive control) |
USD 110.00 |
|
LY423561 | Transient overexpression lysate of syndecan 1 (SDC1), transcript variant 1 |
USD 360.00 |
|
TP723929 | Human CD138 Protein, hFc-His Tag |
USD 520.00 |
|
TP762314 | Purified recombinant protein of Human syndecan 1 (SDC1), transcript variant 1, Thr68-Ser233, with N-terminal His tag, expressed in E.coli, 50ug |
USD 205.00 |
USD 379.00