Macrophage Inflammatory Protein 3 (CCL23) (NM_145898) Human Recombinant Protein
CAT#: TP720600
Purified recombinant protein of Human chemokine (C-C motif) ligand 23 (CCL23), transcript variant CKbeta8
Product Images
Specifications
Product Data | |
Species | Human |
Expression Host | E. coli |
Expression cDNA Clone or AA Sequence |
Arg22-Asn120
|
Tag | Tag Free |
Predicted MW | 11.5 kDa |
Concentration | lot specific |
Purity | Greater than 98.0% as determined by RP-HPLC. >95% as determined by SDS-PAGE and Coomassie blue staining |
Buffer | Lyophilized from a 0.2 um filtered solution of 20mM PB, 250mM NaCl, pH 7.2. |
Endotoxin | Endotoxin level is < 0.1 ng/µg of protein (< 1 EU/µg) |
Reconstitution | Always centrifuge tubes before opening. Do not mix by vortex or pipetting. Dissolve the lyophilized protein in ddH2O. It is not recommended to reconstitute a concentration less than 100 µg/ml. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
Storage | Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months. |
Stability | Stable for at least 6 months from date of receipt under proper storage and handling conditions. |
Reference Data | |
RefSeq | NP_665905 |
Locus ID | 6368 |
UniProt ID | P55773 |
Cytogenetics | 17q12 |
Refseq Size | 604 |
Refseq ORF | 360 |
Synonyms | CK-BETA-8; Ckb-8; Ckb-8-1; CKb8; hmrp-2a; MIP-3; MIP3; MPIF-1; SCYA23 |
Summary | This gene is one of several chemokine genes clustered on the q-arm of chromosome 17. Chemokines form a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes. The superfamily is divided into four subfamilies based on the arrangement of the N-terminal cysteine residues of the mature peptide. This chemokine, a member of the CC subfamily, displays chemotactic activity on resting T lymphocytes and monocytes, lower activity on neutrophils and no activity on activated T lymphocytes. The protein is also a strong suppressor of colony formation by a multipotential hematopoietic progenitor cell line. In addition, the product of this gene is a potent agonist of the chemokine (C-C motif) receptor 1. Alternative splicing results in multiple transcript variants that encode different isoforms. [provided by RefSeq, Jul 2013] |
Protein Families | Druggable Genome, Secreted Protein |
Protein Pathways | Chemokine signaling pathway, Cytokine-cytokine receptor interaction |
Documents
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Resources
Recombinant Protein Resources |
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
LC407835 | CCL23 HEK293T cell transient overexpression lysate (as WB positive control) |
USD 134.00 |
|
LY407835 | Transient overexpression lysate of chemokine (C-C motif) ligand 23 (CCL23), transcript variant CKbeta8 |
USD 436.00 |
|
PH310897 | CCL23 MS Standard C13 and N15-labeled recombinant protein (NP_665905) |
USD 3,255.00 |
|
TP310897 | Recombinant protein of human chemokine (C-C motif) ligand 23 (CCL23), transcript variant CKbeta8, 20 µg |
USD 867.00 |
|
TP723836 | Purified recombinant protein of Human chemokine (C-C motif) ligand 23 (CCL23 / MPIF-1), transcript variant CKbeta8 |
USD 330.00 |
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