Cathepsin D (CTSD) (NM_001909) Human Recombinant Protein

CAT#: TP720341

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Recombinant protein of human cathepsin D (CTSD)


 Product Datasheet for 'TP720341'

  View other "CTSD" proteins (4)

USD 299.00


Availability*
2 Weeks

Size
    • 10 ug


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Specifications

Product Data
Description Recombinant protein of human cathepsin D (CTSD)
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence A DNA sequence from TrueORF clone, RC200719, encoding the full length protein of human CTSD
Tag C-His
Predicted MW 43.8 kDa
Concentration >50 ug/mL as determined by microplate BCA method
Purity >95% as determined by SDS-PAGE and Coomassie blue staining
Buffer 20mM MES, 150mM NaCl, pH 5.5.
Endotoxin < 0.1 EU per µg protein as determined by LAL test
Reference Data
RefSeq NP_001900
Locus ID 1509
Refseq Size 2141
Cytogenetics 11p15.5
Refseq ORF 1236
Synonyms CLN10; CPSD; HEL-S-130P
Summary This gene encodes a member of the A1 family of peptidases. The encoded preproprotein is proteolytically processed to generate multiple protein products. These products include the cathepsin D light and heavy chains, which heterodimerize to form the mature enzyme. This enzyme exhibits pepsin-like activity and plays a role in protein turnover and in the proteolytic activation of hormones and growth factors. Mutations in this gene play a causal role in neuronal ceroid lipofuscinosis-10 and may be involved in the pathogenesis of several other diseases, including breast cancer and possibly Alzheimer's disease. [provided by RefSeq, Nov 2015]
Protein Families Druggable Genome, Protease
Protein Pathways Lysosome

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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