p18 INK4c (CDKN2C) (NM_001262) Human Recombinant Protein
Recombinant protein of human cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) (CDKN2C), transcript variant 1
Product Datasheet for 'TP720216'
Specifications
Product Data | |
Description | Recombinant protein of human cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) (CDKN2C), transcript variant 1 |
Species | Human |
Expression Host | E. coli |
Tag | C-His |
Predicted MW | 20.3 kDa |
Concentration | Resuspend the protein to the desired concentration in proper buffer. |
Purity | >95% as determined by SDS-PAGE and Coomassie blue staining |
Buffer | Lyophilized from a 0.2 µM filtered solution of 20mM Phosphate buffer, 150mM NaCl, pH 8.0. |
Endotoxin | < 0.1 EU per µg protein as determined by LAL test |
Reference Data | |
RefSeq | NP_001253 |
Locus ID | 1031 |
Refseq Size | 2104 |
Cytogenetics | 1p32.3 |
Refseq ORF | 504 |
Synonyms | INK4C; p18; p18-INK4C |
Summary | The protein encoded by this gene is a member of the INK4 family of cyclin-dependent kinase inhibitors. This protein has been shown to interact with CDK4 or CDK6, and prevent the activation of the CDK kinases, thus function as a cell growth regulator that controls cell cycle G1 progression. Ectopic expression of this gene was shown to suppress the growth of human cells in a manner that appears to correlate with the presence of a wild-type RB1 function. Studies in the knockout mice suggested the roles of this gene in regulating spermatogenesis, as well as in suppressing tumorigenesis. Two alternatively spliced transcript variants of this gene, which encode an identical protein, have been reported. [provided by RefSeq, Jul 2008] |
Protein Families | Druggable Genome |
Protein Pathways | Cell cycle |
Documents
FAQs |
SDS |
Resources
Protein Resources |
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
LY409196 | Transient overexpression lysate of cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) (CDKN2C), transcript variant 2 |
USD 315.00 |
|
LY420041 | Transient overexpression lysate of cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) (CDKN2C), transcript variant 1 |
USD 315.00 |
|
LC810042 | CDKN2C-knockout Cell lysate from HeLa cell ine, one vial of parental cell line lysate included as control |
USD 495.00 |
|
TP314412 | Recombinant protein of human cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) (CDKN2C), transcript variant 2 |
USD 748.00 |
|
TP313083 | Recombinant protein of human cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) (CDKN2C), transcript variant 1 |
USD 748.00 |
|
LC429933 | CDKN2C HEK293T cell transient overexpression lysate (as WB positive control) |
USD 95.00 |
|
LC420041 | CDKN2C HEK293T cell transient overexpression lysate (as WB positive control) |
USD 95.00 |
|
PH313083 | CDKN2C MS Standard C13 and N15-labeled recombinant protein (NP_001253) |
USD 1,995.00 |
|
LC409196 | CDKN2C HEK293T cell transient overexpression lysate (as WB positive control) |
USD 95.00 |
|
LY429933 | Transient overexpression lysate of cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) (CDKN2C), transcript variant 2 |
USD 315.00 |
|
PH314412 | CDKN2C MS Standard C13 and N15-labeled recombinant protein (NP_523240) |
USD 1,995.00 |
USD 379.00