MGMT (NM_002412) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC229131L3V

  • LentiORF®

Lenti ORF particles, MGMT (Myc-DDK tagged) - Human O-6-methylguanine-DNA methyltransferase (MGMT), 200ul, >10^7 TU/mL

ORF Plasmid: DDK tGFP

Lentiviral Particles: DDK DDK w/ Puro mGFP mGFP w/ Puro


Buy this product and get 50% off on the Lenti RapidTiter kit. Use Code: Rapid50

USD 1,000.00

7 Weeks*

Size
    • 200 ul

Product Images

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Specifications

Product Data
Type Human Tagged ORF Clone Lentiviral Particle
Tag Myc-DDK
Symbol MGMT
Mammalian Cell Selection Puromycin
Vector pLenti-C-Myc-DDK-P2A-Puro
ACCN NM_002412
ORF Size 714 bp
Sequence Data
The ORF insert of this clone is exactly the same as(RC229131).
OTI Disclaimer The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
OTI Annotation This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
Reference Data
RefSeq NM_002412.3
RefSeq ORF 624 bp
Locus ID 4255
UniProt ID P16455
Cytogenetics 10q26.3
Domains Methyltransf_1
Protein Families Druggable Genome
MW 24.9 kDa
Gene Summary Alkylating agents are potent carcinogens that can result in cell death, mutation and cancer. The protein encoded by this gene is a DNA repair protein that is involved in cellular defense against mutagenesis and toxicity from alkylating agents. The protein catalyzes transfer of methyl groups from O(6)-alkylguanine and other methylated moieties of the DNA to its own molecule, which repairs the toxic lesions. Methylation of the genes promoter has been associated with several cancer types, including colorectal cancer, lung cancer, lymphoma and glioblastoma. [provided by RefSeq, Sep 2015]

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.