WWOX (NM_016373) Human Tagged ORF Clone Lentiviral Particle
CAT#: RC220747L1V
- LentiORF®
Lenti ORF particles, WWOX (Myc-DDK tagged) - Human WW domain containing oxidoreductase (WWOX), transcript variant 1, 200ul, >10^7 TU/mL
Lentiviral Particles: DDK w/ Puro mGFP mGFP w/ Puro
AAV Particle: DDK
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Specifications
Product Data | |
Type | Human Tagged ORF Clone Lentiviral Particle |
Tag | Myc-DDK |
Symbol | WWOX |
Synonyms | D16S432E; DEE28; EIEE28; FOR; FRA16D; HHCMA56; PRO0128; SCAR12; SDR41C1; WOX1 |
Mammalian Cell Selection | None |
Vector | pLenti-C-Myc-DDK |
ACCN | NM_016373 |
ORF Size | 1242 bp |
Sequence Data |
The ORF insert of this clone is exactly the same as(RC220747).
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OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_016373.1 |
RefSeq Size | 2264 bp |
RefSeq ORF | 1245 bp |
Locus ID | 51741 |
UniProt ID | Q9NZC7 |
Cytogenetics | 16q23.1-q23.2 |
Domains | WW, adh_short |
Protein Families | Druggable Genome |
MW | 46.5 kDa |
Gene Summary | This gene encodes a member of the short-chain dehydrogenases/reductases (SDR) protein family. This gene spans the FRA16D common chromosomal fragile site and appears to function as a tumor suppressor gene. Expression of the encoded protein is able to induce apoptosis, while defects in this gene are associated with multiple types of cancer. Disruption of this gene is also associated with autosomal recessive spinocerebellar ataxia 12. Disruption of a similar gene in mouse results in impaired steroidogenesis, additionally suggesting a metabolic function for the protein. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2014] |
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