HIP55 (DBNL) (NM_014063) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC203435L1V

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  • LentiORF®

Lenti ORF particles, DBNL (Myc-DDK tagged) - Human drebrin-like (DBNL), transcript variant 1, 200ul, >10^7 TU/mL



USD 1,007.00


Availability*
6 Weeks

Size
    • 200 ul


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Specifications

Product Data
Type Human Tagged ORF Clone Lentiviral Particle
Tag Myc-DDK
Symbol DBNL
Synonyms ABP1; HIP-55; HIP55; SH3P7
Mammalian Cell Selection None
Vector pLenti-C-Myc-DDK
ACCN NM_014063
ORF Size 1293 bp
Sequence Data
The ORF insert of this clone is exactly the same as(RC203435).
OTI Disclaimer The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
OTI Annotation This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
Reference Data
RefSeq NM_014063.5
RefSeq Size 2213 bp
RefSeq ORF 1296 bp
Locus ID 28988
UniProt ID Q9UJU6
Cytogenetics 7p13
Domains SH3, ADF
MW 48.3 kDa
Gene Summary Adapter protein that binds F-actin and DNM1, and thereby plays a role in receptor-mediated endocytosis. Plays a role in the reorganization of the actin cytoskeleton, formation of cell projections, such as neurites, in neuron morphogenesis and synapse formation via its interaction with WASL and COBL. Does not bind G-actin and promote actin polymerization by itself. Required for the formation of organized podosome rosettes (By similarity). May act as a common effector of antigen receptor-signaling pathways in leukocytes. Acts as a key component of the immunological synapse that regulates T-cell activation by bridging TCRs and the actin cytoskeleton to gene activation and endocytic processes.[UniProtKB/Swiss-Prot Function]
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.