SOX2 (NM_003106) Human Tagged ORF Clone Lentiviral Particle
CAT#: RC200757L2V
- LentiORF®
Lenti ORF particles, SOX2 (mGFP-tagged) - Human SRY (sex determining region Y)-box 2 (SOX2), 200ul, >10^7 TU/mL
Lentiviral Particles: DDK DDK w/ Puro mGFP w/ Puro
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Specifications
Product Data | |
Type | Human Tagged ORF Clone Lentiviral Particle |
Tag | mGFP |
Symbol | SOX2 |
Synonyms | ANOP3; MCOPS3 |
Mammalian Cell Selection | None |
Vector | pLenti-C-mGFP |
ACCN | NM_003106 |
ORF Size | 951 bp |
Sequence Data |
The ORF insert of this clone is exactly the same as(RC200757).
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OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_003106.2 |
RefSeq Size | 2520 bp |
RefSeq ORF | 954 bp |
Locus ID | 6657 |
UniProt ID | P48431 |
Cytogenetics | 3q26.33 |
Protein Families | Adult stem cells, Cancer stem cells, Embryonic stem cells, ES Cell Differentiation/IPS, Induced pluripotent stem cells, Transcription Factors |
MW | 34.3 kDa |
Gene Summary | This intronless gene encodes a member of the SRY-related HMG-box (SOX) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate. The product of this gene is required for stem-cell maintenance in the central nervous system, and also regulates gene expression in the stomach. Mutations in this gene have been associated with optic nerve hypoplasia and with syndromic microphthalmia, a severe form of structural eye malformation. This gene lies within an intron of another gene called SOX2 overlapping transcript (SOX2OT). [provided by RefSeq, Jul 2008] |
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