RNase H1 (RNASEH1) (NM_002936) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC200595L1V

  • LentiORF®

Lenti ORF particles, RNASEH1 (Myc-DDK tagged) - Human ribonuclease H1 (RNASEH1), 200ul, >10^7 TU/mL

ORF Plasmid: DDK tGFP

Lentiviral Particles: DDK DDK w/ Puro mGFP mGFP w/ Puro

AAV Particle: DDK

Buy this product and get 50% off on the Lenti RapidTiter kit. Use Code: Rapid50

USD 850.00

2 Weeks*

    • 200 ul

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Product Data
Type Human Tagged ORF Clone Lentiviral Particle
Tag Myc-DDK
Symbol RNASEH1
Synonyms H1RNA; PEOB2; RNH1
Mammalian Cell Selection None
Vector pLenti-C-Myc-DDK
ACCN NM_002936
ORF Size 858 bp
Sequence Data
The ORF insert of this clone is exactly the same as(RC200595).
OTI Disclaimer The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
OTI Annotation This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
Reference Data
RefSeq NM_002936.3
RefSeq Size 1865 bp
RefSeq ORF 861 bp
Locus ID 246243
UniProt ID O60930
Cytogenetics 2p25.3
Domains rnaseH
Protein Pathways DNA replication
MW 32.1 kDa
Gene Summary This gene encodes an endonuclease that specifically degrades the RNA of RNA-DNA hybrids and plays a key role in DNA replication and repair. Alternate in-frame start codon initiation results in the production of alternate isoforms that are directed to the mitochondria or to the nucleus. The production of the mitochondrial isoform is modulated by an upstream open reading frame (uORF). Mutations in this gene have been found in individuals with progressive external ophthalmoplegia with mitochondrial DNA deletions, autosomal recessive 2. Alternative splicing results in additional coding and non-coding transcript variants. Pseudogenes of this gene have been defined on chromosomes 2 and 17. [provided by RefSeq, Jul 2017]

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