IFNAR1 (NM_000629) Human Untagged Clone

CAT#: SC324178

IFNAR1 (untagged)-Human interferon (alpha, beta and omega) receptor 1 (IFNAR1)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: IFNAR1
• Synonyms: AVP; IFN-alpha-REC; IFNAR; IFNBR; IFRC
• Vector: pCMV6-AC
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_000629.2 CTTAGGACGGGGCGATGGCGGCTGAGAGGAGCTGCGCGTGCGCGAACATGTAACTGGTGG
  GATCTGCGGCGGCTCCCAGATGATGGTCGTCCTCCTGGGCGCGACGACCCTAGTGCTCGT
  CGCCGTGGCGCCATGGGTGTTGTCCGCAGCCGCAGGTGGAAAAAATCTAAAATCTCCTCA
  AAAAGTAGAGGTCGACATCATAGATGACAACTTTATCCTGAGGTGGAACAGGAGCGATGA
  GTCTGTCGGGAATGTGACTTTTTCATTCGATTATCAAAAAACTGGGATGGATAATTGGAT
  AAAATTGTCTGGGTGTCAGAATATTACTAGTACCAAATGCAACTTTTCTTCACTCAAGCT
  GAATGTTTATGAAGAAATTAAATTGCGTATAAGAGCAGAAAAAGAAAACACTTCTTCATG
  GTATGAGGTTGACTCATTTACACCATTTCGCAAAGCTCAGATTGGTCCTCCAGAAGTACA
  TTTAGAAGCTGAAGATAAGGCAATAGTGATACACATCTCTCCTGGAACAAAAGATAGTGT
  TATGTGGGCTTTGGATGGTTTAAGCTTTACATATAGCTTAGTTATCTGGAAAAACTCTTC
  AGGTGTAGAAGAAAGGATTGAAAATATTTATTCCAGACATAAAATTTATAAACTCTCACC
  AGAGACTACTTATTGTCTAAAAGTTAAAGCAGCACTACTTACGTCATGGAAAATTGGTGT
  CTATAGTCCAGTACATTGTATAAAGACCACAGTTGAAAATGAACTACCTCCACCAGAAAA
  TATAGAAGTCAGTGTCCAAAATCAGAACTATGTTCTTAAATGGGATTATACATATGCAAA
  CATGACCTTTCAAGTTCAGTGGCTCCACGCCTTTTTAAAAAGGAATCCTGGAAACCATTT
  GTATAAATGGAAACAAATACCTGACTGTGAAAATGTCAAAACTACCCAGTGTGTCTTTCC
  TCAAAACGTTTTCCAAAAAGGAATTTACCTTCTCCGCGTACAAGCATCTGATGGAAATAA
  CACATCTTTTTGGTCTGAAGAGATAAAGTTTGATACTGAAATACAAGCTTTCCTACTTCC
  TCCAGTCTTTAACATTAGATCCCTTAGTGATTCATTCCATATCTATATCGGTGCTCCAAA
  ACAGTCTGGAAACACGCCTGTGATCCAGGATTATCCACTGATTTATGAAATTATTTTTTG
  GGAAAACACTTCAAATGCTGAGAGAAAAATTATCGAGAAAAAAACTGATGTTACAGTTCC
  TAATTTGAAACCACTGACTGTATATTGTGTGAAAGCCAGAGCACACACCATGGATGAAAA
  GCTGAATAAAAGCAGTGTTTTTAGTGACGCTGTATGTGAGAAAACAAAACCAGGAAATAC
  CTCTAAAATTTGGCTTATAGTTGGAATTTGTATTGCATTATTTGCTCTCCCGTTTGTCAT
  TTATGCTGCGAAAGTCTTCTTGAGATGCATCAATTATGTCTTCTTTCCATCACTTAAACC
  TTCTTCCAGTATAGATGAGTATTTCTCTGAACAGCCATTGAAGAATCTTCTGCTTTCAAC
  TTCTGAGGAACAAATCGAAAAATGTTTCATAATTGAAAATATAAGCACAATTGCTACAGT
  AGAAGAAACTAATCAAACTGATGAAGATCATAAAAAATACAGTTCCCAAACTAGCCAAGA
  TTCAGGAAATTATTCTAATGAAGATGAAAGCGAAAGTAAAACAAGTGAAGAACTACAGCA
  GGACTTTGTATGACCAGAAATGAACTGTGTCAAGTATAAGGTTTTTCAGCAGGAGTTACA
  CTGGGAGCCTGAGGTCCTCACCTTCCTCTCAGTAACTACAGAGAGGACGTTTCCCTGTTT
  AGGGAAAGAAAAAACATCTTCAGATCATAGGTCCTAAAAATACGGGCAAGCTCTTAACTA
  TTTAAAAATGAAATTACAGGCCCGGGCACGGTGGCTCACACCTGTAATCCCAGCACTTTG
  GGAGGCTGAGGCAGGCAGATCATGAGGTCAAGAGATCGAGACCAGCCTGGCCAACGTGGT
  GAAACCCCATCTCTACTAAAAAAAAAAAAAAA
• Restriction Sites: ECoRI-NOT
• ACCN: NM_000629
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_000629.2, NP_000620.2
• RefSeq Size: 6099 bp
• RefSeq ORF: 1674 bp
• Locus ID: 3454
• UniProt ID: P17181
• Cytogenetics: 21q22.11
• Protein Families: Druggable Genome, Transmembrane
• Protein Pathways: Cytokine-cytokine receptor interaction, Jak-STAT signaling pathway, Natural killer cell mediated cytotoxicity, Toll-like receptor signaling pathway
• Gene Summary: The protein encoded by this gene is a type I membrane protein that forms one of the two chains of a receptor for interferons alpha and beta. Binding and activation of the receptor stimulates Janus protein kinases, which in turn phosphorylate several proteins, including STAT1 and STAT2. The protein belongs to the type II cytokine receptor family and functions as an antiviral factor. [provided by RefSeq, Jul 2020]