IFNAR1 (NM_000629) Human Untagged Clone

CAT#: SC119799

IFNAR1 (untagged)-Human interferon (alpha, beta and omega) receptor 1 (IFNAR1)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: IFNAR1
• Synonyms: AVP; IFN-alpha-REC; IFNAR; IFNBR; IFRC
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_000629, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGATGGTCGTCCTCCTGGGCGCGACGACCCTAGTGCTCGTCGCCGTGGCGCCATGGGTGTTGTCCGCAG
  CCGCAGGTGGAAAAAATCTAAAATCTCCTCAAAAAGTAGAGGTCGACATCATAGATGACAACTTTATCCT
  GAGGTGGAACAGGAGCGATGAGTCTGTCGGGAATGTGACTTTTTCATTCGATTATCAAAAAACTGGGATG
  GATAATTGGATAAAATTGTCTGGGTGTCAGAATATTACTAGTACCAAATGCAACTTTTCTTCACTCAAGC
  TGAATGTTTATGAAGAAATTAAATTGCGTATAAGAGCAGAAAAAGAAAACACTTCTTCATGGTATGAGGT
  TGACTCATTTACACCATTTCGCAAAGCTCAGATTGGTCCTCCAGAAGTACATTTAGAAGCTGAAGATAAG
  GCAATAGTGATACACATCTCTCCTGGAACAAAAGATAGTGTTATGTGGGCTTTGGATGGTTTAAGCTTTA
  CATATAGCTTAGTTATCTGGAAAAACTCTTCAGGTGTAGAAGAAAGGATTGAAAATATTTATTCCAGACA
  TAAAATTTATAAACTCTCACCAGAGACTACTTATTGTCTAAAAGTTAAAGCAGCACTACTTACGTCATGG
  AAAATTGGTGTCTATAGTCCAGTACATTGTATAAAGACCACAGTTGAAAATGAACTACCTCCACCAGAAA
  ATATAGAAGTCAGTGTCCAAAATCAGAACTATGTTCTTAAATGGGATTATACATATGCAAACATGACCTT
  TCAAGTTCAGTGGCTCCACGCCTTTTTAAAAAGGAATCCTGGAAACCATTTGTATAAATGGAAACAAATA
  CCTGACTGTGAAAATGTCAAAACTACCCAGTGTGTCTTTCCTCAAAACGTTTTCCAAAAAGGAATTTACC
  TTCTCCGCGTACAAGCATCTGATGGAAATAACACATCTTTTTGGTCTGAAGAGATAAAGTTTGATACTGA
  AATACAAGCTTTCCTACTTCCTCCAGTCTTTAACATTAGATCCCTTAGTGATTCATTCCATATCTATATC
  GGTGCTCCAAAACAGTCTGGAAACACGCCTGTGATCCAGGATTATCCACTGATTTATGAAATTATTTTTT
  GGGAAAACACTTCAAATGCTGAGAGAAAAATTATCGAGAAAAAAACTGATGTTACAGTTCCTAATTTGAA
  ACCACTGACTGTATATTGTGTGAAAGCCAGAGCACACACCATGGATGAAAAGCTGAATAAAAGCAGTGTT
  TTTAGTGACGCTGTATGTGAGAAAACAAAACCAGGAAATACCTCTAAAATTTGGCTTATAGTTGGAATTT
  GTATTGCATTATTTGCTCTCCCGTTTGTCATTTATGCTGCGAAAGTCTTCTTGAGATGCATCAATTATGT
  CTTCTTTCCATCACTTAAACCTTCTTCCAGTATAGATGAGTATTTCTCTGAACAGCCATTGAAGAATCTT
  CTGCTTTCAACTTCTGAGGAACAAATCGAAAAATGTTTCATAATTGAAAATATAAGCACAATTGCTACAG
  TAGAAGAAACTAATCAAACTGATGAAGATCATAAAAAATACAGTTCCCAAACTAGCCAAGATTCAGGAAA
  TTATTCTAATGAAGATGAAAGCGAAAGTAAAACAAGTGAAGAACTACAGCAGGACTTTGTATGA
  
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_000629 unedited
  GGTCGATTTTGTATACGACTCCTATAGGGCGGCCGCGATTCGGCACGAGGGCGGCTGAGA
  GGAGCTGCGCGTGCGCNGACATGTAACTGGTGGGATCTGCGGCGGCTCCCAGATGATGGT
  CGTCCTCCTGGGCGCGACGACCCTAGTGCTCGTCGCCGTGGCGCCATGGGTGTTGTCCGC
  AGCCGCAGGTGGAAAAAATCTAAAATCTCCTCAAAAAGTAGAGGTCGACATCATAGATGA
  CAACTTTATCCTGAGGTGGAACAGGAGCGATGAGTCTGTCGGGAATGTGACTTTTTCATT
  CGATTATCAAAAAACTGGGATGGATAATTGGATAAAATTGTCTGGGTGTCAGAATATTAC
  TAGTACCAAATGCAACTTTTCTTCACTCAAGCTGAATGTTTATGAAGAAATTAAATTGCG
  TATAAGAGCAGAAAAAGAAAACACTTCTTCATGGTATGAGGTTGACTCATTTACACCATT
  TCGCAAAGCTCAGATTGGTCCTCCAGAAGTACATTTAGAAGCTGAAGATAAGGCAATAGT
  GATACACATCTCTCCTGGAACAAAAGATAGTGTTATGTGGGCTTTGGATGGTTTAAGCTT
  TACATATAGCTTACTTATCTGGAAAAACTCTTCAGGTGTAGAAGAAAGGATTGAAAATAT
  TTATTCCAGACATAAAATTTATAAACTCTCACCAGAGACTACTTATTGTCTAAAAGTTAA
  AGCAGCACTACTTACGTCATGNGAAATTGGTGTCTATAGTCCAGTACATTGTATAAAGAC
  CCACAGTTGAAAATGAACTACCTTCACCAGAATNATTAGAAGATCAGTGTCCAAATCANA
  ACTATGTTCTTANATGGGGATTATACATATNGCAACATGACTCTTCAAGGTTCCAGTGGC
  TCCACGCCTTTTTTAAAAGGNATCCTGNAAACATT
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_000629 unedited
  GGCCGCAATTTAGAGTCGAGTTTTTTTTTTTTTTTTTTGTCTCAACTCTTTTAATTTCTT
  TTTTTAAAGAGTCTCACGCTGTCACCAGGCTGGAGTGCAGTGGCGTGATCTCGGCTCACT
  GCAACCTCCACCTCCTGTTTTCAAGCGATTCTCCTGCCTCAGCCTCCTGAGTAGCTAAGA
  CAACAGGCGCGCGCCACCACACCCGGCTAATTTTTGTATTTTTAGTAGAGATGGGGTTTC
  ACCACGTTGGCCAGGCTGGTCTCGATCTCTTGACCTCATGATCTGCCTGCCTCAGCCTCC
  CAAAGTGCTGGGATTACAGGTGTGAGCCACCGTGCCCGGGCCTGTAATTTCATTTTTAAA
  TAGTTAAGAGCTTGCCCGTATTTTTAGGACCTATGATCTGAAGATGTTTTTTCTTTCCCT
  AAACAGGGAAACGTCCTCTCTGTAGTTACTGAGAGGAAGGTGAGGACCTCAGGCTCCCAG
  TGTAACTCCTGCTGAAAAACCTTATACTTGACACAGTTCATTTCTGGTCATACAAAGTCC
  TGCTGTAGTTCTTCACTTGTTTTACTTTCGCTTTCATCTTCATTAGAATAATTTCCTGAA
  TCTTGGCTAGTTTGGGAACTGTATTTTTTATGATCTTCATCAGTTTGATTAGTTTCTTCT
  ACTGTAGCAATTGTGCTTATATTTTCAATTATGAAACATTTTTCGATTTGTTCCTCAGAA
  GTTGAAAGCAGAAGATTCTTCAATGGCTGTTCAGAGAAATACTCATCTATACTGGGAAGA
  AGGGTTTAGTGATGGAAAGAAGACATAATTGATGCATCTCAAGAAGACTTTCGCAGCATA
  AATGACAAACGGNAGAGCCAATAATGGCATACAAATTNCCACTATNAGCCCAATTTTAGA
  GGTATTCCTGGTTTTGTTTCCTAACTACAGCGTCACTAAAAAAACTGCTTTATTCANCTT
  TCATACATGGNGNGGGCTCTGGCCTTCACCN
  
• Restriction Sites: ECoRI-NOT
• ACCN: NM_000629
• Insert Size: 2390 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_000629.2, NP_000620.2
• RefSeq Size: 6099 bp
• RefSeq ORF: 1674 bp
• Locus ID: 3454
• UniProt ID: P17181
• Cytogenetics: 21q22.11
• Protein Families: Druggable Genome, Transmembrane
• Protein Pathways: Cytokine-cytokine receptor interaction, Jak-STAT signaling pathway, Natural killer cell mediated cytotoxicity, Toll-like receptor signaling pathway
• Gene Summary: The protein encoded by this gene is a type I membrane protein that forms one of the two chains of a receptor for interferons alpha and beta. Binding and activation of the receptor stimulates Janus protein kinases, which in turn phosphorylate several proteins, including STAT1 and STAT2. The protein belongs to the type II cytokine receptor family and functions as an antiviral factor. [provided by RefSeq, Jul 2020]