ADAM23 (NM_003812) Human Untagged Clone

CAT#: SC117782

ADAM23 (untagged)-Human ADAM metallopeptidase domain 23 (ADAM23)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: ADAM23
• Synonyms: MDC-3; MDC3
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_003812, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGAAGCCGCCCGGCAGCAGCTCGCGGCAGCCGCCCCTGGCGGGCTGCAGCCTTGCCGGCGCTTCCTGCG
  GCCCCCAACGCGGCCCCGCCGGCTCGGTGCCTGCCAGCGCCCCGGCCCGCACGCCGCCCTGCCGCCTGCT
  TCTCGTCCTTCTCCTGCTGCCTCCGCTCGCCGCCTCGTCCCGGCCCCGCGCCTGGGGGGCTGCTGCGCCC
  AGCGCTCCGCATTGGAATGAAACTGCAGAAAAAAATTTGGGAGTCCTGGCAGATGAAGACAATACATTGC
  AACAGAATAGCAGCAGTAATATCAGTTACAGCAATGCAATGCAGAAAGAAATCACACTGCCTTCAAGACT
  CATATATTACATCAACCAAGACTCGGAAAGCCCTTATCACGTTCTTGACACAAAGGCAAGACACCAGCAA
  AAACATAATAAGGCTGTCCATCTGGCCCAGGCAAGCTTCCAGATTGAAGCCTTCGGCTCCAAATTCATTC
  TTGACCTCATACTGAACAATGGTTTGTTGTCTTCTGATTATGTGGAGATTCACTACGAAAATGGGAAACC
  ACAGTACTCTAAGGGTGGAGAGCACTGTTACTACCATGGAAGCATCAGAGGCGTCAAAGACTCCAAGGTG
  GCTCTGTCAACCTGCAATGGACTTCATGGCATGTTTGAAGATGATACCTTCGTGTATATGATAGAGCCAC
  TAGAGCTGGTTCATGATGAGAAAAGCACAGGTCGACCACATATAATCCAGAAAACCTTGGCAGGACAGTA
  TTCTAAGCAAATGAAGAATCTCACTATGGAAAGAGGTGACCAGTGGCCCTTTCTCTCTGAATTACAGTGG
  TTGAAAAGAAGGAAGAGAGCAGTGAATCCATCACGTGGTATATTTGAAGAAATGAAATATTTGGAACTTA
  TGATTGTTAATGATCACAAAACGTATAAGAAGCATCGCTCTTCTCATGCACATACCAACAACTTTGCAAA
  GTCCGTGGTCAACCTTGTGGATTCTATTTACAAGGAGCAGCTCAACACCAGGGTTGTCCTGGTGGCTGTA
  GAGACCTGGACTGAGAAGGATCAGATTGACATCACCACCAACCCTGTGCAGATGCTCCATGAGTTCTCAA
  AATACCGGCAGCGCATTAAGCAGCATGCTGATGCTGTGCACCTCATCTCGCGGGTGACATTTCACTATAA
  GAGAAGCAGTCTGAGTTACTTTGGAGGTGTCTGTTCTCGCACAAGAGGAGTTGGTGTGAATGAGTATGGT
  CTTCCAATGGCAGTGGCACAAGTATTATCGCAGAGCCTGGCTCAAAACCTTGGAATCCAATGGGAACCTT
  CTAGCAGAAAGCCAAAATGTGACTGCACAGAATCCTGGGGTGGCTGCATCATGGAGGAAACAGGGGTGTC
  CCATTCTCGAAAATTTTCAAAGTGCAGCATTTTGGAGTATAGAGACTTTTTACAGAGAGGAGGTGGAGCC
  TGCCTTTTCAACAGGCCAACAAAGCTATTTGAGCCCACGGAATGTGGAAATGGATACGTGGAAGCTGGGG
  AGGAGTGTGATTGTGGTTTTCATGTGGAATGCTATGGATTATGCTGTAAGAAATGTTCCCTCTCCAACGG
  GGCTCACTGCAGCGACGGGCCCTGCTGTAACAATACCTCATGTCTTTTTCAGCCACGAGGGTATGAATGC
  CGGGATGCTGTGAACGAGTGTGATATTACTGAATATTGTACTGGAGACTCTGGTCAGTGCCCACCAAATC
  TTCATAAGCAAGACGGATATGCATGCAATCAAAATCAGGGCCGCTGCTACAATGGCGAGTGCAAGACCAG
  AGACAACCAGTGTCAGTACATCTGGGGAACAAAGGCTGCAGGGTCTGACAAGTTCTGCTATGAAAAGCTG
  AATACAGAAGGCACTGAGAAGGGAAACTGCGGGAAGGATGGAGACCGGTGGATTCAGTGCAGCAAACATG
  ATGTGTTCTGTGGATTCTTACTCTGTACCAATCTTACTCGAGCTCCACGTATTGGTCAACTTCAGGGTGA
  GATCATTCCAACTTCCTTCTACCATCAAGGCCGGGTGATTGACTGCAGTGGTGCCCATGTAGTTTTAGAT
  GATGATACGGATGTGGGCTATGTAGAAGATGGAACGCCATGTGGCCCGTCTATGATGTGTTTAGATCGGA
  AGTGCCTACAAATTCAAGCCCTAAATATGAGCAGCTGTCCACTCGATTCCAAGGGTAAAGTCTGTTCGGG
  CCATGGGGTGTGTAGTAATGAAGCCACCTGCATTTGTGATTTCACCTGGGCAGGGACAGATTGCAGTATC
  CGGGATCCAGTTAGGAACCTTCACCCCCCCAAGGATGAAGGACCCAAGGGTCCTAGTGCCACCAATCTCA
  TAATAGGCTCCATCGCTGGTGCCATCCTGGTAGCAGCTATTGTCCTTGGGGGCACAGGCTGGGGATTTAA
  AAATGTCAAGAAGAGAAGGTTCGATCCTACTCAGCAAGGCCCCATCTGA
  
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_003812 unedited
  TGTGCGAGGATATTATGTNAACACGNATTTCACTATCAGGGNCGGAACGCCCAATTCGGC
  ACGAGGGCCCGGCGGCAGCCCCCGCAGTCGCTGAAGCGGCCGCGCCCGCCGGGGGAGGGA
  GTAGCCGCTGGGGAGGCTCCAAGTTGGCGGAGCGGCGAGGACCCCTGGACTCCTCTGCGT
  CCCGCCCCGGGAGTGGCTGCGAGGCTAGGCGAGCCGGGAAAGTTGTTCCGCCCAGCCCCG
  AGCCCCGCGCCCCGTGCCCCGAGCCCGGAGCCCCCTGCCCGCCGCGGCACCATGCGCGCC
  GAGCCGGCGTGACCGGCTCCGCCCGCGGCCGCCCCGCAGCTAGCCCGGCGCTCTCGCCGG
  CCACACGGAGCGGCGCCCGGGAGCTATGAGCCATGAAGCCGCCCGGCAGCAGCTCGCGGC
  AGCCGCCCCTGGCGGGCTGCAGCCTTGCCGGCGCTTCCTGCGGCCCCCAACGCGGCCCCG
  CCGGCTCGGTGCCTGCCAGCGCCCCGGCCCGCACGCCGCCCTGCCGCCTGCTTCTCGTAC
  TTCTACTGCTGCCTCCGCTCGCCGCCTAGTCCCGGCCCCGCGCCTGGGGGGCTGCTGCGC
  CCCACGCTCCGCATTGGAATGAAACTGCAGAAACAAATCCGGGAGTCCTGGCCGATGAAG
  ACCATACCTTGCAACCAGATAGCAGCCGTAATATCCGTTACAGCCATGCACTGCAGAAAG
  CAATCACCCTGCCTTCAAGACTTATATATTACATCAACCAAGACTTGGCAAGCCCCTATC
  ACGTTCTTGACCCAAAGCCAGACACCGCCAAAACATAATAAGGCTGTCCATCCGGCCCAG
  CAAGCTTCCAGATGGAGCCCTCGGCTCCAAATTACTCTTGACCTCATACGAACCAAGGTT
  CGTGGCTTCCCGACTAGTCGGAN
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_003812 unedited
  GCGGCCGCAATCTAGGATCGAGTTTTTTTTTTTTTTTTTTAATGATTCCTTTATTGCATT
  TAATTTTTGTGTGTGTGTTGTTCCTTCGTCCATTAGGGAAAAAAAAGATCTGGAACAGTT
  CTTTTTATAGCATGGTCTTTTGCCCCCTCCCCCGTTTACTGACAGGTGGTGAAAGGTGTT
  CTTTGACATTATTTCCAAAAGAGACAGTTTTCTTTTACCCCATCCTTGTCACCCCAACTT
  TAGCTCCGTAGTCATTACCACCCAAAGGTTTTGTTTACAAACTTAATAGTTCCAGTAACA
  CTGCTGCGAGTATGTCATACCCAGAATCCAACAGTGCAAGGCGGTGTCCATCCAGCGCAG
  CTGATTCAGATGGGGCCTTGCTGAGTAGGATCGAACCTTCTCTTCTTGACATTTTTAAAT
  CCCCAGCCTGTGCCCCCAAGGACAATAGCTGCTACCAGGATGGCACCAGCGATGGAGCCT
  ATTATGAGATTGGTGGCACTAGGACCCTTGGGTCCTTCATCCTTGGGGGGGTGAAGGTTC
  CTAACTGGATCCCGGATACTGCAATCTGTCCCTGCCCAGGTGAAATCACAAATGCAGGTG
  GCTTCATTACTACACACCCCATGGCCCGAACAGACTTTACCCTTGGAATCGAGTGGACAG
  CTGCTCATATTTAGGGCTTGAATTTGTANGCACTTCCGATCTAAACACATCATAGACGGG
  CCACATGGCGTTCCATCTTCTACATAGCCCACATCCGTATCATCATCTAAAACTACATGG
  GCACCACTGCAGTCAATCACCCCGCCTTGATGGTANAAGGAAGTGGAATGATTCTACCCT
  GAAGTGACCAATACGTGGAGCTCGAGTAAGATTGGCCAGAGTAAGATCCACAGACACATC
  TGTTTGCTGCACTGATCCCCGGNCTCATCTTNCCGAG
  
• Restriction Sites: NotI-NotI
• ACCN: NM_003812
• Insert Size: 2900 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_003812.2, NP_003803.1
• RefSeq Size: 3059 bp
• RefSeq ORF: 2499 bp
• Locus ID: 8745
• UniProt ID: O75077
• Cytogenetics: 2q33.3
• Domains: Reprolysin, DISIN, Pep_M12B_propep, ACR
• Protein Families: Druggable Genome, Protease, Secreted Protein, Transmembrane
• Gene Summary: This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. It is reported that inactivation of this gene is associated with tumorigenesis in human cancers. [provided by RefSeq, May 2013]