LGALS3BP (NM_005567) Human Tagged ORF Clone

CAT#: RC204918

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LGALS3BP (Myc-DDK-tagged)-Human lectin, galactoside-binding, soluble, 3 binding protein (LGALS3BP)



  "NM_005567" in other vectors (6)

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USD 480.00


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Size
    • 10 ug


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Specifications

Product Data
Product Name LGALS3BP (NM_005567) Human Tagged ORF Clone
Type Human Tagged ORF Clone
Tag Myc-DDK
Symbol LGALS3BP
Synonyms 90K; BTBD17B; CyCAP; gp90; M2BP; MAC-2-BP; TANGO10B
Vector pCMV6-Entry
E. coli Selection Kanamycin (25 ug/mL)
Cell Selection Neomycin
Sequence Data
>RC204918 ORF sequence
Red=Cloning site Blue=ORF Green=Tags(s)

TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
GCCGCGATCGCC

ATGACCCCTCCGAGGCTCTTCTGGGTGTGGCTGCTGGTTGCAGGAACCCAAGGCGTGAACGATGGTGACA
TGCGGCTGGCCGATGGGGGCGCCACCAACCAGGGCCGCGTGGAGATCTTCTACAGAGGCCAGTGGGGCAC
TGTGTGTGACAACCTGTGGGACCTGACTGATGCCAGCGTCGTCTGCCGGGCCCTGGGCTTCGAGAACGCC
ACCCAGGCTCTGGGCAGAGCTGCCTTCGGGCAAGGATCAGGCCCCATCATGCTGGACGAGGTCCAGTGCA
CGGGAACCGAGGCCTCACTGGCCGACTGCAAGTCCCTGGGCTGGCTGAAGAGCAACTGCAGGCACGAGAG
AGACGCTGGTGTGGTCTGCACCAATGAAACCAGGAGCACCCACACCCTGGACCTCTCCAGGGAGCTCTCG
GAGGCCCTTGGCCAGATCTTTGACAGCCAGCGGGGCTGCGACCTGTCCATCAGCGTGAATGTGCAGGGCG
AGGACGCCCTGGGCTTCTGTGGCCACACGGTCATCCTGACTGCCAACCTGGAGGCCCAGGCCCTGTGGAA
GGAGCCGGGCAGCAATGTCACCATGAGTGTGGATGCTGAGTGTGTGCCCATGGTCAGGGACCTTCTCAGG
TACTTCTACTCCCGAAGGATTGACATCACCCTGTCGTCAGTCAAGTGCTTCCACAAGCTGGCCTCTGCCT
ATGGGGCCAGGCAGCTGCAGGGCTACTGCGCAAGCCTCTTTGCCATCCTCCTCCCCCAGGACCCCTCGTT
CCAGATGCCCCTGGACCTGTATGCCTATGCAGTGGCCACAGGGGACGCCCTGCTGGAGAAGCTCTGCCTA
CAGTTCCTGGCCTGGAACTTCGAGGCCTTGACGCAGGCCGAGGCCTGGCCCAGTGTCCCCACAGACCTGC
TCCAACTGCTGCTGCCCAGGAGCGACCTGGCGGTGCCCAGCGAGCTGGCCCTACTGAAGGCCGTGGACAC
CTGGAGCTGGGGGGAGCGTGCCTCCCATGAGGAGGTGGAGGGCTTGGTGGAGAAGATCCGCTTCCCCATG
ATGCTCCCTGAGGAGCTCTTTGAGCTGCAGTTCAACCTGTCCCTGTACTGGAGCCACGAGGCCCTGTTCC
AGAAGAAGACTCTGCAGGCCCTGGAATTCCACACTGTGCCCTTCCAGTTGCTGGCCCGGTACAAAGGCCT
GAACCTCACCGAGGATACCTACAAGCCCCGGATTTACACCTCGCCCACCTGGAGTGCCTTTGTGACAGAC
AGTTCCTGGAGTGCACGGAAGTCACAACTGGTCTATCAGTCCAGACGGGGGCCTTTGGTCAAATATTCTT
CTGATTACTTCCAAGCCCCCTCTGACTACAGATACTACCCCTACCAGTCCTTCCAGACTCCACAACACCC
CAGCTTCCTCTTCCAGGACAAGAGGGTGTCCTGGTCCCTGGTCTACCTCCCCACCATCCAGAGCTGCTGG
AACTACGGCTTCTCCTGCTCCTCGGACGAGCTCCCTGTCCTGGGCCTCACCAAGTCTGGCGGCTCAGATC
GCACCATTGCCTACGAAAACAAAGCCCTGATGCTCTGCGAAGGGCTCTTCGTGGCAGACGTCACCGATTT
CGAGGGCTGGAAGGCTGCGATTCCCAGTGCCCTGGACACCAACAGCTCGAAGAGCACCTCCTCCTTCCCC
TGCCCGGCAGGGCACTTCAACGGCTTCCGCACGGTCATCCGCCCCTTCTACCTGACCAACTCCTCAGGTG
TGGAC


ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
ACAAGGATGACGACGATAAG
GTTTAA
>RC204918 protein sequence
Red=Cloning site Green=Tags(s)

MTPPRLFWVWLLVAGTQGVNDGDMRLADGGATNQGRVEIFYRGQWGTVCDNLWDLTDASVVCRALGFENA
TQALGRAAFGQGSGPIMLDEVQCTGTEASLADCKSLGWLKSNCRHERDAGVVCTNETRSTHTLDLSRELS
EALGQIFDSQRGCDLSISVNVQGEDALGFCGHTVILTANLEAQALWKEPGSNVTMSVDAECVPMVRDLLR
YFYSRRIDITLSSVKCFHKLASAYGARQLQGYCASLFAILLPQDPSFQMPLDLYAYAVATGDALLEKLCL
QFLAWNFEALTQAEAWPSVPTDLLQLLLPRSDLAVPSELALLKAVDTWSWGERASHEEVEGLVEKIRFPM
MLPEELFELQFNLSLYWSHEALFQKKTLQALEFHTVPFQLLARYKGLNLTEDTYKPRIYTSPTWSAFVTD
SSWSARKSQLVYQSRRGPLVKYSSDYFQAPSDYRYYPYQSFQTPQHPSFLFQDKRVSWSLVYLPTIQSCW
NYGFSCSSDELPVLGLTKSGGSDRTIAYENKALMLCEGLFVADVTDFEGWKAAIPSALDTNSSKSTSSFP
CPAGHFNGFRTVIRPFYLTNSSGVD

TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Restriction Sites SgfI-MluI      Cloning Scheme for this gene      Plasmid Map     
ACCN NM_005567
ORF Size 1755 bp
OTI Disclaimer Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.

The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
OTI Annotation This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
Product Components The ORF clone is ion-exchange column purified, transfection-ready dried plasmid DNA, and shipped with 2 vector sequencing primers.
Reconstitution 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Reference Data
RefSeq NM_005567.2, NP_005558.1
RefSeq Size 2277 bp
RefSeq ORF 1758 bp
Locus ID 3959
Cytogenetics 17q25.3
Domains SR
Protein Families Druggable Genome, Secreted Protein
MW 65.3 kDa
Gene Summary The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. LGALS3BP has been found elevated in the serum of patients with cancer and in those infected by the human immunodeficiency virus (HIV). It appears to be implicated in immune response associated with natural killer (NK) and lymphokine-activated killer (LAK) cell cytotoxicity. Using fluorescence in situ hybridization the full length 90K cDNA has been localized to chromosome 17q25. The native protein binds specifically to a human macrophage-associated lectin known as Mac-2 and also binds galectin 1. [provided by RefSeq, Jul 2008]

Citations (2)

Other Versions

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