p27 KIP 1(CDKN1B) (NM_004064) Human Tagged ORF Clone

CAT#: RC201661

CDKN1B (Myc-DDK-tagged)-Human cyclin-dependent kinase inhibitor 1B (p27, Kip1) (CDKN1B)

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USD 98.00

USD 390.00

In Stock

    • 10 ug

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Product Data
Product Name p27 KIP 1(CDKN1B) (NM_004064) Human Tagged ORF Clone
Symbol CDKN1B
Synonyms CDKN4; KIP1; MEN1B; MEN4; P27KIP1
Vector pCMV6-Entry
Sequence Data
ORF Nucleotide Sequence
>RC201661 representing NM_004064
Red=Cloning site Blue=ORF Green=Tags(s)



Protein Sequence
>RC201661 representing NM_004064
Red=Cloning site Green=Tags(s)


Sequencher program is needed, download here.
Restriction Sites SgfI-MluI      Cloning Scheme for this gene      Plasmid Map     
Tag Myc-DDK
ACCN NM_004064
ORF Size 594 bp
OTI Disclaimer Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.

The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
OTI Annotation This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
Product Components The ORF clone is ion-exchange column purified, transfection-ready dried plasmid DNA, and shipped with 2 vector sequencing primers.
Reference Data
RefSeq NM_004064.1, NM_004064.2, NM_004064.3, NM_004064.4, NP_004055
RefSeq Size 2422
RefSeq ORF 597
Locus ID 1027
Cytogenetics 12p13.1
Domains CDI
Protein Families Druggable Genome
Protein Pathways ErbB signaling pathway, Cell cycle, Pathways in cancer, Prostate cancer, Chronic myeloid leukemia, Small cell lung cancer
MW 21.9 kDa
Gene Summary This gene encodes a cyclin-dependent kinase inhibitor, which shares a limited similarity with CDK inhibitor CDKN1A/p21. The encoded protein binds to and prevents the activation of cyclin E-CDK2 or cyclin D-CDK4 complexes, and thus controls the cell cycle progression at G1. The degradation of this protein, which is triggered by its CDK dependent phosphorylation and subsequent ubiquitination by SCF complexes, is required for the cellular transition from quiescence to the proliferative state. Mutations in this gene are associated with multiple endocrine neoplasia type IV (MEN4). [provided by RefSeq, Apr 2014]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.