Human Properdin (CFP) ELISA KIT (1 x 96 wells)
CAT#: EA102466
For Quantitative Detection of human Properdin in cell culture supernates, serum and plasma (heparin, EDTA).
USD 705.00
3 Weeks*
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Specifications
Product Data | |
Format | 8x12 divisible strips |
Assay Type | Sandwich ELISA kit of Quantitative Detection for Human Properdin |
Assay Length | 3.5 hours incubations; 1 hour washing and analyzing samples |
Signal | Colorimetric |
Curve Range | 312pg/ml-20000pg/ml |
Specificity | This kit is used for quantitative detection of Human Properdin |
Sensitivity | <10pg/ml |
Reactivities | Human |
Cross Reactivity | There is no detectable cross-reactivity with other relevant proteins. |
Components |
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Background | Properdin or Factor P is the only known positive regulator of complement activation that stabilizes thealternative pathway convertases. This gene encodes a plasma glycoprotein that positively regulates the alternative complement pathway of the innate immune system. This protein binds to many microbial surfaces and apoptotic cells and stabilizes the C3- and C5-convertase enzyme complexes in a feedback loop that ultimately leads to formation of the membrane attack complex and lysis of the target cell. Mutations in this gene result in two forms of properdin deficiency, which results in high susceptibility to meningococcal infections. Multiple alternatively spliced variants, encoding the same protein, have been identified. |
Gene Symbol | CFP |
Gene ID | 5199 |
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.